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上肢动脉动脉瘤在肯尼亚人群中的发生情况。

Aneurysms in the arteries of the upper extremity in a Kenyan population.

机构信息

Department of Human Anatomy, University of Nairobi, PO Box 00100, Nairobi 30197, Kenya.

出版信息

Cardiovasc Pathol. 2011 Jan-Feb;20(1):e53-6. doi: 10.1016/j.carpath.2010.01.009. Epub 2010 Feb 2.

Abstract

BACKGROUND

Aneurysms in the arteries of the upper extremity are rare but important in predicting aortic aneurysms and their potential to thromboembolize and cause limb loss. Their localization, age, and gender distribution vary between countries depending on ethnic background and cause. These data are valuable in the management of aneurysms, but are largely lacking from the Kenyan population.

OBJECTIVE

This study aimed at examining the pattern of these aneurysms in a Kenyan population.

STUDY DESIGN

Retrospective.

SETTING

Kenyatta National Hospital, Kenya.

PATIENTS AND METHODS

Hospital records of aneurysms in upper limb arteries over 10 years from January 1998 to December 2007 were examined. Ethical approval was given by the Kenyatta National Hospital Ethics and Research Committee. Site, age, gender, and risk factors were recorded. Unconfirmed diagnoses were excluded. Results were analyzed using SPSS 11.50 and presented using tables.

RESULTS

Aneurysms of the upper extremity arteries comprise 34 (35.4%) out of 96 peripheral aneurysms. Of these, brachial artery was the most common site (35.3%), followed by brachiocephalic (11, 32.4%), subclavian (9, 26.5%), radial (1, 2.9%), and anterior interosseous (1, 2.9%). Trauma was the commonest predisposing factor (41.2%), followed by atherosclerosis and related comorbidities (32.4%), infection (11.8%), and autoimmune disease (8.8%). The mean age was 39.5 years (range: 13-79) with a variable gender distribution.

CONCLUSION

Aneurysms of the upper extremity arteries are not uncommon in the Kenyan population. They occur more commonly in individuals aged 50 years and less, and although most of them are traumatic, atherosclerosis constitutes a significant proportion. Prudent management of risk factors is recommended.

摘要

背景

上肢动脉的动脉瘤虽少见,但对预测主动脉瘤及其发生血栓栓塞和导致肢体丧失的潜在风险非常重要。它们的定位、年龄和性别分布因种族背景和病因的不同而在不同国家有所差异。这些数据对于动脉瘤的管理很有价值,但在肯尼亚人群中却基本缺乏。

目的

本研究旨在检查肯尼亚人群中这些动脉瘤的模式。

研究设计

回顾性研究。

地点

肯尼亚肯雅塔国家医院。

患者和方法

检查了 1998 年 1 月至 2007 年 12 月 10 年间上肢动脉的动脉瘤的医院记录。肯雅塔国家医院伦理和研究委员会批准了该研究。记录了发病部位、年龄、性别和危险因素。排除了未经证实的诊断。使用 SPSS 11.50 分析结果,并以表格形式呈现。

结果

上肢动脉的动脉瘤占 96 例外周动脉瘤中的 34 例(35.4%)。其中,肱动脉最常见(35.3%),其次是头臂干(11 例,32.4%)、锁骨下动脉(9 例,26.5%)、桡动脉(1 例,2.9%)和骨间前动脉(1 例,2.9%)。创伤是最常见的诱发因素(41.2%),其次是动脉粥样硬化及相关合并症(32.4%)、感染(11.8%)和自身免疫性疾病(8.8%)。平均年龄为 39.5 岁(范围:13-79 岁),性别分布差异较大。

结论

上肢动脉的动脉瘤在肯尼亚人群中并不少见。它们更常见于 50 岁及以下的个体,尽管大多数是创伤性的,但动脉粥样硬化构成了相当大的比例。建议谨慎管理危险因素。

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