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自发性真性肱动脉瘤:来自索马里的一例病例报告。

Spontaneous true brachial artery aneurysm: A case report from Somalia.

作者信息

Ali Abdijalil Abdullahi, Hussein Abdinafic Mohamud, Abdi Hassan Kalif, Siyad Ali Abdulkadir Ali, Keilie Ali Mohamed Warsame, Ahmed Fatima Mohamud

机构信息

Department of Cardiovascular Surgery at Mogadishu Somalia Türkiye Training and Research Hospital, Mogadishu, Somalia.

Department of Cardiovascular Surgery at Mogadishu Somalia Türkiye Training and Research Hospital, Mogadishu, Somalia.

出版信息

Int J Surg Case Rep. 2025 Feb;127:110866. doi: 10.1016/j.ijscr.2025.110866. Epub 2025 Jan 14.

Abstract

INTRODUCTION AND IMPORTANCE

True brachial artery aneurysms are rather uncommon, due to their number of etiological factors. Besides inducing symptoms such as hand or digit ischemia, they may present as pulsative tumefactions and cause pain or paresthesias through nerve impingement. The diagnosis is based on duplex ultrasonography, CTA in the operational planning phase, and a physical examination.

CASE PRESENTATION

A 28 year old female patient was attending our center with pain and swelling of the left arm because of a brachial artery aneurysm. The patient underwent successful excision of the aneurysmal sac followed by brachial artery reconstruction with a prosthetic graft.

CLINICAL DISCUSSION

Brachial artery aneurysms are defined as dilation greater than 50 % of the normal diameter. The pathophysiologic mechanism of brachial artery aneurysms involves local hemodynamic factors such as increased flow that lead to endothelial production of nitric oxide and reactive oxygen species, resulting in upregulation of matrix metalloproteinase production and damage to the arterial wall.

CONCLUSION

There is some evidence linking the creation of an AVF with the occurrence of BAA. Immunosuppression might also add to the charter of risk factors leading to aneurysmal events. Surgical repair is generally the method of choice although in selected cases, the endovascular approach may be employed. When an autologous vein is not available, the use of a synthetic graft may be a reasonable option when performing artery reconstruction.

摘要

引言与重要性

真性肱动脉瘤较为罕见,因其病因众多。除了引发手部或手指缺血等症状外,它们还可能表现为搏动性肿块,并通过神经受压导致疼痛或感觉异常。诊断基于双功超声、手术规划阶段的CTA以及体格检查。

病例介绍

一名28岁女性患者因肱动脉瘤就诊于我们中心,其左臂疼痛且肿胀。患者成功切除动脉瘤囊,随后用人工血管进行肱动脉重建。

临床讨论

肱动脉瘤定义为直径扩张超过正常直径的50%。肱动脉瘤的病理生理机制涉及局部血流动力学因素,如血流增加导致内皮细胞产生一氧化氮和活性氧,进而导致基质金属蛋白酶生成上调和动脉壁损伤。

结论

有一些证据表明动静脉内瘘的建立与肱动脉瘤的发生有关。免疫抑制也可能增加导致动脉瘤事件的危险因素。手术修复通常是首选方法,尽管在某些特定情况下可采用血管内治疗方法。当无法使用自体静脉时,在进行动脉重建时使用人工血管可能是一个合理的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58c3/11788792/c108956f6918/gr1.jpg

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