Czabanski Robert, Jezewski Michal, Wrobel Janusz, Jezewski Janusz, Horoba Krzysztof
Institute of Electronics, Division of Biomedical Electronics, Silesian University of Technology, Gliwice 44-100, Poland.
IEEE Trans Inf Technol Biomed. 2010 Jul;14(4):1062-74. doi: 10.1109/TITB.2009.2039644. Epub 2010 Feb 2.
Cardiotocography (CTG) is a biophysical method of fetal condition assessment based mainly on recording and automated analysis of fetal heart activity. The computerized fetal monitoring systems provide the quantitative description of the CTG signals, but the effective conclusion generation methods for decision process support are still needed. Assessment of the fetal state can be verified only after delivery using the fetal (newborn) outcome data. One of the most important features defining the abnormal fetal outcome is low birth weight. This paper describes an application of the artificial neural network based on logical interpretation of fuzzy if-then rules neurofuzzy system to evaluate the risk of low-fetal birth weight using the quantitative description of CTG signals. We applied different learning procedures integrating least squares method, deterministic annealing (DA) algorithm, and epsilon-insensitive learning, as well as various methods of input dataset modification. The performance was evaluated with the number of correctly classified cases (CC) expressed as the percentage of the testing set size, and with overall index (OI) being the function of predictive indexes. The best classification efficiency (CC = 97.5% and OI = 82.7%), was achieved for integrated DA with epsilon-insensitive learning and dataset comprising of the CTG traces recorded as earliest for a given patient. The obtained results confirm efficiency for supporting the fetal outcome prediction using the proposed methods.
胎心监护(CTG)是一种评估胎儿状况的生物物理方法,主要基于对胎儿心脏活动的记录和自动分析。计算机化的胎儿监护系统提供了CTG信号的定量描述,但仍需要有效的结论生成方法来支持决策过程。只有在分娩后使用胎儿(新生儿)结局数据才能验证对胎儿状态的评估。定义异常胎儿结局的最重要特征之一是低出生体重。本文描述了一种基于模糊if-then规则神经模糊系统逻辑解释的人工神经网络的应用,用于使用CTG信号的定量描述来评估低出生体重胎儿的风险。我们应用了不同的学习程序,整合了最小二乘法、确定性退火(DA)算法和ε-不敏感学习,以及各种输入数据集修改方法。使用正确分类病例数(CC)作为测试集大小的百分比来评估性能,并使用总体指标(OI)作为预测指标的函数。对于整合了DA和ε-不敏感学习以及由给定患者最早记录的CTG轨迹组成的数据集,实现了最佳分类效率(CC = 97.5%,OI = 82.7%)。获得的结果证实了使用所提出的方法支持胎儿结局预测的有效性。