年龄相关性黄斑变性低视力患者的暗点位移与最佳视网膜部位之间的关系。

The relationship between scotoma displacement and preferred retinal loci in low-vision patients with age-related macular degeneration.

机构信息

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.

出版信息

Can J Ophthalmol. 2010 Feb;45(1):58-61. doi: 10.3129/i09-244.

DOI:10.3129/i09-244

PMID:20130712

Abstract

OBJECTIVE

Adaptive strategies in low-vision patients with age-related macular degeneration use preferred retinal loci (PRLs) for the purpose of achieving better visual function. In the process of redirecting the eye toward the PRL, central scotomata are displaced eccentrically. The consequential effect of the first on the second may offer an indirect method for PRL identification. The purpose of this study was to clarify the relationship between scotoma displacement and PRL location.

DESIGN

Prospective, nonrandomized, observational case series.

PARTICIPANTS

Forty-one adults with a confirmed diagnosis of age-related macular degeneration.

METHODS

Scotoma characteristics were obtained with automated perimetry. PRL topography was obtained with the Nidek MP-1 instrument. Outcome measures selected for this study were scotoma displacement and PRL eccentricities estimates.

RESULTS

We tested 16 males and 25 females aged 70-98 years (mean 82.5 [SD 6.71] years) with best-corrected visual acuity of 0.81 (SD 0.24) logMar units (20/128). PRL location logically matched scotoma displacement in 30 study subjects (73.17%, p < 0.00432). In this subgroup (n = 30), PRL eccentricity (5.55 [SD 3.35] degrees ) was almost identical to scotoma displacement eccentricity (5.22 [SD 1.98] degrees )(p < 0.65).

CONCLUSIONS

Scotoma displacement recorded with macular perimetry methods offers reasonable indirect estimates of PRL location.

摘要

目的

年龄相关性黄斑变性的低视力患者采用首选视网膜部位（PRL）来获得更好的视觉功能，这需要他们对眼球进行适应策略。在将眼球重新引导至 PRL 的过程中，中心暗点会发生偏心移位。第一个暗点对第二个暗点的影响可能为 PRL 的识别提供一种间接方法。本研究的目的是阐明暗点移位与 PRL 位置之间的关系。

设计

前瞻性、非随机、观察性病例系列研究。

参与者

41 名经确诊患有年龄相关性黄斑变性的成年人。

方法

通过自动视野计获取暗点特征。使用 Nidek MP-1 仪器获取 PRL 地形图。本研究选择的评估指标为暗点移位和 PRL 偏心率估计值。

结果

我们共检测了 16 名男性和 25 名女性，年龄为 70-98 岁（平均 82.5 [6.71]岁），最佳矫正视力为 0.81（0.24 对数视力表单位）（20/128）。在 30 名研究对象中（73.17%，p < 0.00432），PRL 位置与暗点移位逻辑上相匹配。在这个亚组（n = 30）中，PRL 偏心率（5.55 [3.35]度）几乎与暗点移位偏心率（5.22 [1.98]度）相同（p < 0.65）。