Renkin J, Wijns W, Hanet C, Michel X, Cosyns J, Col J
Department of Intensive Care, University of Louvain Medical School, Brussels, Belgium.
Cathet Cardiovasc Diagn. 1991 Mar;22(3):167-73. doi: 10.1002/ccd.1810220303.
Percutaneous transluminal angioplasty (PTCA) of coronary stenoses involving major bifurcations carries a small but significant risk of side branch occlusion which can be avoided by simultaneously using multiple dilatation systems. Among 1,275 PTCA procedures performed between 1984 and 1988 in 1,035 consecutive patients, 42 double wire procedures were applied (4%) to protect and/or dilate major coronary side branches. A total of 80 coronary stenoses were attempted of which 76 were located on a bifurcation and 4 on other segments. In the first 11 patients (group A), 2 guiding catheters were used and PTCA of each vessel was successfully performed by means of separate double lumen over-the-wire balloon catheters. In the next 31 patients (group B), 2 guidewires were advanced through a single guiding catheter and PTCA was attempted using "Monorail" balloon catheters sequentially advanced over the wires. In group B, a successful PTCA was obtained in 29 patients (93%) but twisting of the wires hampered balloon progression in 5 cases, such that dilatation could only be performed by stepping back to a single wire technique. The procedure time in group B was significantly shorter than in group A: 144 +/- 30 versus 230 +/- 52 minutes (p = .01). Repeat angiography was performed in 35 out of 40 patients (87%) after a mean of 180 +/- 46 days following successful PTCA. Angiographic restenosis was present in 37% (24/65) of bifurcation segments which, in our experience, is not significantly different from the angiographic restenosis rate in less complex lesions (248/740; 34%; NS).(ABSTRACT TRUNCATED AT 250 WORDS)
涉及主要分支的冠状动脉狭窄的经皮腔内血管成形术(PTCA)存在小但显著的分支闭塞风险,可通过同时使用多个扩张系统来避免。在1984年至1988年期间对1035例连续患者进行的1275例PTCA手术中,应用了42例双线手术(4%)来保护和/或扩张主要冠状动脉分支。共尝试了80处冠状动脉狭窄,其中76处位于分支处,4处位于其他节段。在前11例患者(A组)中,使用了2根引导导管,通过单独的双腔超滑导丝球囊导管成功对每支血管进行了PTCA。在接下来的31例患者(B组)中,2根导丝通过单个引导导管推进,并尝试使用“单轨”球囊导管依次沿导丝推进进行PTCA。在B组中,29例患者(93%)成功进行了PTCA,但5例出现导丝扭曲阻碍球囊推进,以至于只能通过退回单导丝技术进行扩张。B组的手术时间明显短于A组:144±30分钟对230±52分钟(p = 0.01)。40例患者中有35例(87%)在成功PTCA后平均180±46天进行了重复血管造影。分支节段的血管造影再狭窄率为37%(24/65),根据我们的经验,这与不太复杂病变的血管造影再狭窄率(248/740;34%;无显著差异)无明显不同。(摘要截短于250字)