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腹主动脉瘤(AAA)开放修复术后的腹腔间隔室综合征(ACS)

[Abdominal compartment syndrome (ACS) after abdominal aortic aneurysm (AAA) open repair].

作者信息

Bajardi Guido, Pecoraro Felice, Mirabella Domenico, Bracale Umberto Marcello, Bellisi Mario Girolamo

机构信息

Cattedra di Chirurgia Vascolare, Università degli Studi di Palermo.

出版信息

Ann Ital Chir. 2009 Sep-Oct;80(5):369-74.

Abstract

INTRODUCTION

The Abdominal Compartment Syndrome (ACS) is a "condition in which increased tissue pressure in a confined anatomic space, causes decreased blood flow leading to ischaemia and organic dysfunction and may lead to permanent impairment of function".

MATERIALS AND METHODS

Between June 2007 and June 2008 all patients recovered to our Institution for Abdominal Aortic Aneurysm (AAA) underwent intermittent intra-abdominal pressure monitoring using intra-vescical catheter. Pressure data were registered before abdominal incision, during intervention, at closure of abdominal wall and at 6, 12, 24 and 36 hours in post-operative course. Rise in Intra-Abdominal Pressure (IAP) more then 20 mmHg was considered for surgical decompression.

RESULTS

Twenty three cases of AAA were treated surgically Fourteen underwent elective repair and 9 emergency/urgency repair; in the emergency/urgency group, 8 were symptomatic without rupture signs and one case presented TC rupture signs. In the last case we registered preoperatively IAP more than 20 mmHg treated with only skin tension-free suture. No perioperative mortality was registered.

DISCUSSION

ACS have been increasingly recognized as causes of significant morbidity and mortality over the last years after AAA surgery. ACS was recently classified from the World Society of the Abdominal Compartment Syndrome (WSACS) as primary, secondary and recurrent. ACS was recognized as major prognostic factor after AAA repair. ACS incidence ranges from 4 to 12%. Even if ACS etiological bases are not well known, principal risk factor for ACS development after AAA repair are massive fluid resuscitation infusion and aortic clamping IAP values, and subsequent possibility of ACS development, are superior after ruptured AAA repair than elective repair. Also in our study, even if limited by small number of cases, we registered differences in IAP value during emergency/urgency repair and elective repair. Patients management with rising IAR or at risk of ACS development, should be mandatory decompressed for IAP higher than 20 mmHg or also with inferior values if in association to organ dysfunction. IAP measurement can be performed directly or indirectly and all these techniques have as objective IAP monitoring before its clinical manifestation in ACS.

CONCLUSION

ACS can be considered a reliable predictive factor for aneurysm surgery outcome. Prevention of the ACS, with early recognition of rising IAP and urgent intervention to decompress the tense abdomen can lead to mortality reduction after aneurysm repair. The measurement of IAP is simple and non-invasive, and should be a routine component of physiological monitoring in patients following ruptured aneurysm repair in association with hypotensive hemostasis.

摘要

引言

腹腔间隔室综合征(ACS)是一种“在有限解剖空间内组织压力升高导致血流减少,进而引起缺血和器官功能障碍,并可能导致功能永久性损害的病症”。

材料与方法

2007年6月至2008年6月期间,所有因腹主动脉瘤(AAA)康复后到我院就诊的患者均使用膀胱内导管进行间歇性腹腔内压力监测。在腹部切口前、手术期间、腹壁关闭时以及术后6、12、24和36小时记录压力数据。腹腔内压力(IAP)升高超过20 mmHg时考虑进行手术减压。

结果

23例AAA患者接受了手术治疗,14例行择期修复,9例行急诊/紧急修复;在急诊/紧急修复组中,8例有症状但无破裂迹象,1例出现TC破裂迹象。在最后一例中,我们术前记录到IAP超过20 mmHg,仅采用无张力皮肤缝合进行治疗。未记录到围手术期死亡病例。

讨论

在过去几年中,ACS越来越被认为是AAA手术后严重发病和死亡的原因。最近,世界腹腔间隔室综合征协会(WSACS)将ACS分为原发性、继发性和复发性。ACS被认为是AAA修复后的主要预后因素。ACS的发生率在4%至12%之间。即使ACS的病因基础尚不清楚,AAA修复后ACS发生的主要危险因素是大量液体复苏输注和主动脉钳夹。与择期修复相比,破裂AAA修复后IAP值及随后发生ACS的可能性更高。在我们的研究中,即使受病例数量限制,我们也记录到了急诊/紧急修复和择期修复期间IAP值的差异。对于IAP升高或有发生ACS风险的患者,如果IAP高于20 mmHg或即使IAP值较低但伴有器官功能障碍,都应进行强制性减压。IAP测量可直接或间接进行,所有这些技术的目标都是在ACS临床表现之前进行IAP监测。

结论

ACS可被视为动脉瘤手术结果的可靠预测因素。预防ACS,早期识别IAP升高并紧急干预以减压紧张的腹部,可降低动脉瘤修复后的死亡率。IAP测量简单且无创,应成为破裂动脉瘤修复并伴有低血压止血患者生理监测的常规组成部分。

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