Institute of Organic Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
Org Lett. 2010 Mar 5;12(5):940-3. doi: 10.1021/ol902902m.
The discovery of several fluorescent chemosensors for Hg(II) and Ag(I) in mixed aqueous solution is reported. The ease with which these fluorionophores were prepared from a common core underscores the utility of conformational restriction as a signaling mechanism. In addition, for the first time, significant changes were observed in biarylpyridine emission wavelength, allowing ratiometric detection of Hg(II) and Ag(I). Finally, on the basis of computational analyses, beneficial structural modifications were predicted for the next generation of chemosensors.
本文报道了几种用于混合水溶液中 Hg(II) 和 Ag(I) 的荧光化学传感器的发现。这些荧光团很容易从共同的核心制备，这突出了构象限制作为信号机制的实用性。此外，这还是首次观察到联吡啶发射波长的显著变化，从而可以进行 Hg(II) 和 Ag(I) 的比率检测。最后，基于计算分析，预测了下一代化学传感器的有益结构修饰。
