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Trough infliximab concentration may predict long-term maintenance of infliximab in ankylosing spondylitis.

作者信息

Chu Miow Lin D, Mulleman D, Azzopardi N, Griffoul-Espitalier I, Valat J-P, Paintaud G, Goupille P

出版信息

Scand J Rheumatol. 2010;39(1):97-8. doi: 10.3109/03009740903177745.

DOI:10.3109/03009740903177745
PMID:20132079
Abstract
摘要

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1
Trough infliximab concentration may predict long-term maintenance of infliximab in ankylosing spondylitis.英夫利昔单抗谷浓度可能预测强直性脊柱炎患者英夫利昔单抗的长期维持效果。
Scand J Rheumatol. 2010;39(1):97-8. doi: 10.3109/03009740903177745.
2
Low-dose infliximab treatment for ankylosing spondylitis--clinically- and cost-effective.低剂量英夫利昔单抗治疗强直性脊柱炎——具有临床疗效且成本效益高。
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3
Continuation of treatment with infliximab in ankylosing spondylitis: 2-yr open follow-up.英夫利昔单抗治疗强直性脊柱炎的持续治疗:2年开放性随访。
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4
Switching from infliximab to once-weekly administration of 50 mg etanercept in resistant or intolerant patients with ankylosing spondylitis: results of a fifty-four-week study.在对英夫利昔单抗耐药或不耐受的强直性脊柱炎患者中,将治疗方案转换为每周一次给予50毫克依那西普:一项为期54周的研究结果
Arthritis Rheum. 2006 Oct 15;55(5):812-6. doi: 10.1002/art.22236.
5
Circulating concentration of infliximab and response to treatment in ankylosing spondylitis: results from a randomized control study.英夫利昔单抗的循环浓度与强直性脊柱炎的治疗反应:一项随机对照研究的结果
Arthritis Rheum. 2009 May 15;61(5):569-76. doi: 10.1002/art.24275.
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Therapeutic efficacy and safety of multiple intravenous infusions of infliximab in refractory ankylosing spondylitis patients with axial involvement.英夫利昔单抗多次静脉输注对难治性轴向受累强直性脊柱炎患者的治疗疗效及安全性
Scand J Rheumatol. 2004;33(5):323-6. doi: 10.1080/03009740310004720.
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Infliximab in severe active ankylosing spondylitis with spinal ankylosis.英夫利昔单抗用于伴有脊柱强直的重度活动性强直性脊柱炎。
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Persistent clinical efficacy and safety of anti-tumour necrosis factor alpha therapy with infliximab in patients with ankylosing spondylitis over 5 years: evidence for different types of response.英夫利昔单抗治疗强直性脊柱炎患者5年以上的持续临床疗效和安全性:不同反应类型的证据
Ann Rheum Dis. 2008 Mar;67(3):340-5. doi: 10.1136/ard.2007.075879. Epub 2007 Oct 29.
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Relationship between serum trough infliximab levels, pretreatment C reactive protein levels, and clinical response to infliximab treatment in patients with rheumatoid arthritis.类风湿关节炎患者血清英夫利昔单抗谷浓度水平、治疗前C反应蛋白水平与英夫利昔单抗治疗临床反应之间的关系。
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Sustained effect after lowering high-dose infliximab in patients with rheumatoid arthritis: a prospective dose titration study.类风湿关节炎患者高剂量英夫利昔单抗减量后的持续疗效:一项前瞻性剂量滴定研究。
Ann Rheum Dis. 2008 Dec;67(12):1697-701. doi: 10.1136/ard.2007.083683. Epub 2008 Jan 31.

引用本文的文献

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Pharmaceutics. 2021 Aug 3;13(8):1191. doi: 10.3390/pharmaceutics13081191.
2
Methotrexate effect on immunogenicity and long-term maintenance of adalimumab in axial spondyloarthritis: a multicentric randomised trial.甲氨蝶呤对阿达木单抗治疗中轴型脊柱关节炎的免疫原性和长期维持效果的影响:一项多中心随机试验。
RMD Open. 2020 Jan;6(1). doi: 10.1136/rmdopen-2019-001047. Epub 2020 Jan 9.
3
Therapeutic drug monitoring of infliximab in spondyloarthritis. A review of the literature.
英夫利昔单抗治疗强直性脊柱炎的药物监测:文献综述
Br J Clin Pharmacol. 2019 Oct;85(10):2264-2279. doi: 10.1111/bcp.14062. Epub 2019 Aug 6.
4
Antibodies toward infliximab are associated with low infliximab concentration at treatment initiation and poor infliximab maintenance in rheumatic diseases.针对英夫利昔单抗的抗体与风湿性疾病治疗起始时英夫利昔单抗浓度低和英夫利昔单抗维持治疗效果差有关。
Arthritis Res Ther. 2011 Jun 27;13(3):R105. doi: 10.1186/ar3386.
5
Influence of methotrexate on infliximab pharmacokinetics and pharmacodynamics in ankylosing spondylitis.甲氨蝶呤对强直性脊柱炎患者英夫利昔单抗药代动力学和药效学的影响。
Br J Clin Pharmacol. 2012 Jan;73(1):55-65. doi: 10.1111/j.1365-2125.2011.04050.x.