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当尿液不再有益时:淀粉样变性继发严重肾病综合征的肾动脉栓塞治疗。

When urine is no longer beneficial: renal artery embolisation in severe nephrotic syndrome secondary to amyloidosis.

机构信息

Department of Nephrology, Selcuk University, Meram School of Medicine, Meram, Konya, Turkey.

出版信息

Amyloid. 2010 Mar;17(1):24-6. doi: 10.3109/13506121003619336.

Abstract

Renal artery embolisation (RAE) is an interventional radiology procedure which is used to embolise small branches of renal artery. It is mainly used for urologic purposes, i.e., vascular malformations, angiomyolipomas and renal tumours not amenable to surgical resection. Bilateral RAE can be performed via using absolute ethanol, polyvinyl alcohol or microparticles. After RAE, patients may experience post-embolisation syndrome which is usually self-limited. Use of this procedure for refractory nephrotic syndrome has been rarely defined in the literature to date. Here, we describe a patient who had nephrotic syndrome due to secondary systemic amyloidosis. The patient presented with severe proteinuria (33 g per day), hypoalbuminaemia and anasarca oedema. We applied bilateral RAE with microparticles. We did not observe any complications associated with the procedure. Protein excretion, laboratory values and clinical signs returned to normal.

摘要

肾动脉栓塞术(RAE)是一种介入放射学程序,用于栓塞肾动脉的小分支。它主要用于泌尿科目的,如血管畸形、血管平滑肌脂肪瘤和无法手术切除的肾肿瘤。双侧 RAE 可以通过使用绝对乙醇、聚乙烯醇或微球来进行。RAE 后,患者可能会出现栓塞后综合征,通常是自限性的。迄今为止,该手术在治疗难治性肾病综合征方面在文献中很少被定义。在这里,我们描述了一位因继发性全身性淀粉样变性而患有肾病综合征的患者。该患者表现为严重蛋白尿(每天 33 克)、低白蛋白血症和全身性水肿。我们采用双侧微球栓塞术。我们没有观察到与该手术相关的任何并发症。蛋白排泄、实验室值和临床体征恢复正常。

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