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[严重的、亚急性低磷血症性轴索性多发性神经病]

[Severe, subacute axonal polyneuropathy due to hypophosphatemia].

作者信息

van Eijk Jeroen J J, Abdo W Farid, den Deurwaarder Edwin, Zwarts Machiel J, van de Warrenburg Bart P C

机构信息

Universitair Medisch Centrum St Radboud, Afd. Neurologie, Nijmegen, The Netherlands.

出版信息

Ned Tijdschr Geneeskd. 2010;154:A914.

Abstract

A 46-year-old man receiving tube feeding because of anorexia and weight loss developed progressive neurological symptoms initially resembling Guillain-Barré syndrome. Eventually axonal neuropathy due to severe hypophosphatemia was diagnosed. Hypophosphatemia can be caused by the so-called refeeding syndrome, which may occur in patients who start feeding after prolonged fasting. The neurological manifestations of hypophosphatemia are reversible if oral or intravenous suppletion of phosphate is started in time. Recognizing the refeeding syndrome is crucial in making a timely diagnosis.

摘要

一名46岁男性因厌食和体重减轻接受管饲,起初出现进行性神经症状,类似吉兰-巴雷综合征。最终诊断为严重低磷血症所致的轴索性神经病。低磷血症可由所谓的再喂养综合征引起,该综合征可能发生在长期禁食后开始进食的患者中。如果及时开始口服或静脉补充磷酸盐,低磷血症的神经表现是可逆的。认识到再喂养综合征对于及时诊断至关重要。

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