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内镜检查和内镜超声检查在吞咽困难患者诊断中的价值。

The value of endoscopy and endosonography in the diagnosis of the dysphagic patient.

作者信息

Lorenz R, Jorysz G, Classen M

机构信息

Department of Internal Medicine II, Technical University of Munich, Klinikum Rechts Der Isar, Germany.

出版信息

Dysphagia. 1993;8(2):91-7. doi: 10.1007/BF02266987.

Abstract

The value of endoscopy in dysphagia is limited in the diagnosis of motility disorders and small structures, webs, and hiatal hernias. Endoscopy is of special use for the clarification of an organic cause of dysphagia. Intraluminal tumors can be seen and in a high percentage of cases be definitely diagnosed by taking biopsies; a malignant degeneration in Barrett's esophagus is detectable by endoscopy in 89.1% of cases. Gastroesophageal reflux disease can be diagnosed on endoscopy as it leads to an endoscopically visible inflammatory reaction; however, normal findings on endoscopy cannot exclude reflux disease. Endoscopy is the method of choice in the diagnosis of nonreflux esophagitis, especially Candida and viral esophagitis. A further advantage of endoscopy is the fact that a microscopic diagnosis can be obtained and endoscopic treatment can be performed simultaneously. Submucosal or extramural lesions can be missed by endoscopy. Endosonography, the combination of endoscopy and ultrasonography (EUS) yields additional information in diagnosing submucosal and extramural lesions of the esophagus which is missed by other imaging procedures. One of the main advantages of EUS is the detection of small and submucosal lesions. The most important indication is the local staging of esophageal carcinomas; the accuracy of endosonography in determining the depth of infiltration ranges between 79% and 92%. The detection of paraesophageal lymph nodes is successful in 60%-82%, although EUS cannot differentiate benign from malignant lymph nodes. Submucosal tumors can be visualized by endosonography and their size, echopattern, and the layers of origin can be determined with high accuracy. Further indications for EUS are the exclusion of focal lesions in achalasia or peptic strictures.

摘要

内镜检查在吞咽困难诊断中,对于运动障碍以及小结构、食管蹼和食管裂孔疝的诊断价值有限。内镜检查在明确吞咽困难的器质性病因方面具有特殊用途。腔内肿瘤可见,并且在高比例病例中通过活检可明确诊断;巴雷特食管的恶性化生在内镜检查中89.1%的病例可被检测到。胃食管反流病可通过内镜检查诊断,因为它会导致内镜下可见的炎症反应;然而,内镜检查结果正常不能排除反流病。内镜检查是诊断非反流性食管炎,尤其是念珠菌性和病毒性食管炎的首选方法。内镜检查的另一个优点是能够获得微观诊断并同时进行内镜治疗。内镜检查可能会漏诊黏膜下或壁外病变。内镜超声检查,即内镜与超声检查(EUS)的结合,在诊断食管黏膜下和壁外病变方面可提供其他成像检查所遗漏的额外信息。EUS的主要优点之一是能够检测小的和黏膜下病变。最重要的适应证是食管癌的局部分期;内镜超声检查确定浸润深度的准确率在79%至92%之间。虽然EUS无法区分良性和恶性淋巴结,但检测食管旁淋巴结的成功率为60% - 82%。黏膜下肿瘤可通过内镜超声检查显示,并且可以高精度确定其大小、回声模式和起源层次。EUS的其他适应证包括排除贲门失弛缓症或消化性狭窄中的局灶性病变。

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