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体外心脏震波治疗严重心绞痛之疗效与安全性的双盲及安慰剂对照研究。

Double-blind and placebo-controlled study of the effectiveness and safety of extracorporeal cardiac shock wave therapy for severe angina pectoris.

机构信息

Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.

出版信息

Circ J. 2010 Mar;74(3):589-91. doi: 10.1253/circj.cj-09-1028. Epub 2010 Feb 4.

DOI:10.1253/circj.cj-09-1028
PMID:20134096
Abstract

BACKGROUND

Low-energy shock wave (SW) therapy has improved myocardial ischemia in both a porcine model and in patients with severe angina pectoris.

METHODS AND RESULTS

To further confirm the effectiveness and safety of SW therapy, 8 patients with severe angina pectoris were treated with SW therapy in a double-blind, placebo-controlled and cross-over manner. SW therapy, but not placebo, significantly improved chest pain symptoms and cardiac function without any complications or adverse effects.

CONCLUSIONS

Extracorporeal cardiac SW therapy is an effective, safe and non-invasive therapeutic option for severe angina pectoris.

摘要

背景

低能量冲击波（SW）治疗已改善了猪模型和严重心绞痛患者的心肌缺血。

方法和结果

为了进一步证实 SW 治疗的有效性和安全性，8 名严重心绞痛患者接受了 SW 治疗的双盲、安慰剂对照和交叉试验。SW 治疗，而不是安慰剂，显著改善了胸痛症状和心功能，没有任何并发症或不良反应。

结论

体外心脏 SW 治疗是一种有效、安全和非侵入性的严重心绞痛治疗选择。

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