Houston, Texas From the Department of Plastic Surgery, The University of Texas M. D. Anderson Cancer Center.
Plast Reconstr Surg. 2010 May;125(5):1413-1421. doi: 10.1097/PRS.0b013e3181d62aef.
Although reconstruction of anterior mandibular oncologic defects with bony free flaps is considered the standard method of treatment, the optimal reconstruction of posterior defects is controversial. The authors' goal was to compare outcomes using either a vascularized bone flap or a soft-tissue free flap for posterior mandibular reconstruction.
Data were collected prospectively on 74 patients undergoing posterior mandibular resection including the condyle.
Twenty-four patients underwent vascularized bone flap reconstruction and 50 patients underwent soft-tissue free flap reconstruction. Patients undergoing vascularized bone flap reconstruction were significantly younger than those undergoing soft-tissue free flap reconstruction (47 versus 62 years, respectively; p = 0.0001) and had a lower American Society of Anesthesiologists class (2.6 versus 3.1, respectively; p = 0.001). There were no significant differences in total operative time, intensive care unit stay, or hospital stay. The complication rate was 33 percent for patients receiving vascularized bone flap reconstructions and 38 percent for patients receiving soft-tissue free flap reconstruction (p = 0.70). Mouth opening averaged 39.8 mm for patients with vascularized bone flap reconstructions and 46.4 mm for patients with soft-tissue free flap reconstructions (p = 0.09). Jaw deviation toward the resection side averaged 1.2 mm for vascularized bone flap reconstructions and 5.3 mm for soft-tissue free flap reconstructions (p = 0.02). There was no significant difference in the type of mechanical diet tolerated by either group (p = 0.83).
With careful selection, good reconstructive results after posterior mandibular resection can be achieved with vascularized bone flap or soft-tissue free flaps. In appropriate candidates, vascularized bone flap reconstruction may result in better postoperative occlusion.
尽管使用游离骨瓣重建前下颌骨肿瘤缺损被认为是标准的治疗方法,但后下颌骨缺损的最佳重建方式仍存在争议。作者的目标是比较使用血管化骨瓣或软组织游离皮瓣进行后下颌骨重建的结果。
前瞻性收集 74 例接受下颌骨包括髁突后切除的患者数据。
24 例患者行血管化骨瓣重建,50 例患者行软组织游离皮瓣重建。行血管化骨瓣重建的患者明显比行软组织游离皮瓣重建的患者年轻(分别为 47 岁和 62 岁;p = 0.0001),美国麻醉医师协会(ASA)分级也较低(分别为 2.6 级和 3.1 级;p = 0.001)。总手术时间、重症监护病房停留时间和住院时间无显著差异。血管化骨瓣重建组的并发症发生率为 33%,软组织游离皮瓣重建组为 38%(p = 0.70)。血管化骨瓣重建患者的张口度平均为 39.8mm,软组织游离皮瓣重建患者为 46.4mm(p = 0.09)。血管化骨瓣重建组的下颌骨向切除侧偏斜平均为 1.2mm,软组织游离皮瓣重建组为 5.3mm(p = 0.02)。两组患者对机械饮食的耐受类型无显著差异(p = 0.83)。
经过仔细选择,血管化骨瓣或软组织游离皮瓣均可在后下颌骨切除后获得良好的重建效果。在合适的患者中,血管化骨瓣重建可能会导致更好的术后咬合。