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初步分析下颌骨后外侧重建术后患者报告的结局:皮瓣类型的作用。

A preliminary analysis of patient reported outcomes following posterolateral mandible reconstruction: The role of flap type.

机构信息

Department of Surgery, Plastic and Reconstructive Surgery Division, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

Department of Surgery, Head and Neck Surgery Division, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

出版信息

J Surg Oncol. 2024 Mar;129(3):617-628. doi: 10.1002/jso.27520. Epub 2023 Nov 20.

DOI:10.1002/jso.27520
PMID:37985365
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11457306/
Abstract

BACKGROUND

The choice of tissue type for free flap reconstruction of posterolateral mandible resections is dependent on patient and defect characteristics. We compared clinical and patient-reported outcomes following reconstruction of these defects with a soft tissue or bony free flap.

METHODS

A retrospective review was performed on patients who underwent posterolateral segmental mandibulectomy with immediate free flap reconstruction at MSKCC from 2006 to 2021. Outcomes of interest were patient-reported outcome measures (PROMs) assessed by FACE-Q surveys and complications at the flap recipient site.

RESULTS

Ninety patients received a bony flap and 24 patients received a soft tissue flap. Patients reconstructed with soft tissue flaps had greater rates of composite soft tissue defects (p < 0.0001), condyle resection (p = 0.001), and peripheral vascular disease (p = 0.035). Complication rates were similar between the cohorts (p > 0.05). Bony flaps scored higher on multiple FACE-Q scales: Facial Appearance (p = 0.023) Eating/Drinking (p = 0.029), Smiling (p = 0.012), Speaking (p < 0.001), Swallowing (p = 0.012), Smiling Distress (p = 0.037), and Speaking Distress (p = 0.001).

CONCLUSION

Reconstruction of posterolateral mandibular defects has a similar complication profile when utilizing a bony or soft tissue free flap. Bony flaps may perform better with respect to PROMs. Reconstructive surgeons should consider using bony flap reconstruction to achieve higher patient satisfaction and quality of life.

摘要

背景

游离皮瓣重建下颌后外侧切除术后的组织类型选择取决于患者和缺损的特点。我们比较了这些缺损用软组织或骨游离皮瓣重建后的临床和患者报告的结果。

方法

对 2006 年至 2021 年在 MSKCC 接受后外侧节段下颌骨切除术并立即行游离皮瓣重建的患者进行回顾性研究。感兴趣的结果是通过 FACE-Q 调查评估的患者报告的结果测量(PROM)和皮瓣受区的并发症。

结果

90 例患者接受了骨瓣,24 例患者接受了软组织瓣。接受软组织瓣重建的患者复合软组织缺损的发生率更高(p<0.0001)、髁突切除率(p=0.001)和周围血管疾病(p=0.035)。两组的并发症发生率相似(p>0.05)。在多个 FACE-Q 量表中,骨瓣得分更高:面部外观(p=0.023)、进食/饮水(p=0.029)、微笑(p=0.012)、说话(p<0.001)、吞咽(p=0.012)、微笑困扰(p=0.037)和说话困扰(p=0.001)。

结论

当使用骨或软组织游离皮瓣重建下颌后外侧缺损时,并发症的发生情况相似。骨瓣在 PROM 方面可能表现更好。重建外科医生应考虑使用骨瓣重建以获得更高的患者满意度和生活质量。

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本文引用的文献

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Semin Plast Surg. 2022 Aug 31;36(3):183-191. doi: 10.1055/s-0042-1754386. eCollection 2022 Aug.
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Impact of Neck Disability on Health-Related Quality of Life among Head and Neck Cancer Survivors.颈部残疾对头颈部癌症幸存者健康相关生活质量的影响。
Otolaryngol Head Neck Surg. 2020 Jan;162(1):64-72. doi: 10.1177/0194599819883295. Epub 2019 Oct 15.
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Giving Meaning to Differences in BREAST-Q Scores: Minimal Important Difference for Breast Reconstruction Patients.
赋予 BREAST-Q 评分差异意义:乳房重建患者的最小临床重要差异。
Plast Reconstr Surg. 2020 Jan;145(1):11e-20e. doi: 10.1097/PRS.0000000000006317.
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Challenging the Orthodoxy of Mandibular Reconstructions Comparing Functional Outcomes in Osseous versus Soft Tissue Reconstructions of the Posterolateral Mandible.挑战下颌骨重建的传统观念:比较后外侧下颌骨骨组织与软组织重建的功能结果。
J Reconstr Microsurg. 2020 Jan;36(1):21-27. doi: 10.1055/s-0039-1694044. Epub 2019 Aug 9.
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Quality of life after mandibulectomy: the impact of the resected subsite.颌骨切除术对生活质量的影响:切除部位的影响。
Int J Oral Maxillofac Surg. 2019 Oct;48(10):1273-1278. doi: 10.1016/j.ijom.2019.02.013. Epub 2019 Mar 11.
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Leveraging patient-reported outcomes data to inform oncology clinical decision making: Introducing the FACE-Q Head and Neck Cancer Module.利用患者报告结局数据为肿瘤学临床决策提供信息:引入 FACE-Q 头颈部癌症模块。
Cancer. 2019 Mar 15;125(6):863-872. doi: 10.1002/cncr.31900. Epub 2018 Nov 30.
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Osteocutaneous flaps for head and neck reconstruction: A focused evaluation of donor site morbidity and patient reported outcome measures in different reconstruction options.用于头颈部重建的骨皮瓣:对不同重建方案中供区并发症及患者报告结局指标的重点评估。
Arch Plast Surg. 2018 Nov;45(6):495-503. doi: 10.5999/aps.2017.01592. Epub 2018 Nov 15.
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Mandibular reconstruction.下颌骨重建。
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