Renganathan Arasee, Edwards Robin, Duckett Jonathan R A
Medway Maritime Hospital, London, UK.
Int Urogynecol J. 2010 Jul;21(7):819-21. doi: 10.1007/s00192-010-1101-9. Epub 2010 Feb 5.
Recently, there has been a move towards uterine preserving surgery in the management of pelvic organ prolapse. The negative implications of such surgery have not been delineated. This study aims to identify the risk of finding an unexpected malignancy in these cases.
A database containing details of vaginal hysterectomies performed over a 10-year period was searched. Women who underwent surgery for uterine prolapse were included. Women with other indications for surgery and those who presented with symptoms relating to endometrial or cervical malignancy were excluded. As this is a non-interventional observational study, formal ethical approval was not obtained.
Out of 517 women who underwent a vaginal hysterectomy for prolapse, four cases of endometrial carcinoma were identified giving an incidence of 0.8%.
Conserving a prolapsed uterus without further investigations runs the risk of missing women with endometrial malignancy.
近来，盆腔器官脱垂的治疗出现了向保留子宫手术发展的趋势。此类手术的负面影响尚未明确。本研究旨在确定这些病例中发现意外恶性肿瘤的风险。
检索了一个包含10年间阴道子宫切除术详细信息的数据库。纳入因子宫脱垂接受手术的女性。排除有其他手术指征以及出现与子宫内膜或宫颈恶性肿瘤相关症状的女性。由于这是一项非干预性观察性研究，未获得正式伦理批准。
在517例因脱垂接受阴道子宫切除术的女性中，发现4例子宫内膜癌，发病率为0.8%。
在未进一步检查的情况下保留脱垂的子宫，有漏诊子宫内膜恶性肿瘤患者的风险。
