Snow R T, Fox A R
Department of Otorhinolaryngology, Pontiac Osteopathic Hospital, MI 48058.
J Am Osteopath Assoc. 1991 Feb;91(2):182-4, 187-9.
Mucoepidermoid carcinoma of the larynx is an uncommon malignancy. Nearly all cases are found in middle-aged and elderly men. Most cases arise in the supraglottis. Mucoepidermoid carcinoma is classified histologically as low grade and high grade. The prognosis is relatively good for low-grade tumor and poor for high-grade mucoepidermoid carcinoma, which is also referred to as adenosquamous carcinoma. The treatment is primarily surgical, although the efficacy of post-operative radiation, with and without chemotherapy, is presently under evaluation in a National Intergroup Study. The case reported here is nearly classic for high-grade mucoepidermoid carcinoma, both as to clinical presentation and morphology. This report and discussion are offered to familiarize the reader with this uncommon lesion, of which fewer than 80 cases have been reported.
喉黏液表皮样癌是一种罕见的恶性肿瘤。几乎所有病例都见于中老年男性。大多数病例发生在声门上区。黏液表皮样癌在组织学上分为低级别和高级别。低级别肿瘤的预后相对较好，而高级别黏液表皮样癌（也称为腺鳞癌）的预后较差。治疗主要是手术治疗，不过目前一项全国性多中心研究正在评估术后放疗联合或不联合化疗的疗效。此处报告的病例在临床表现和形态学方面几乎都是高级别黏液表皮样癌的典型病例。提供本报告及讨论是为了让读者熟悉这种罕见病变，目前报告的病例少于80例。
