1 年内镰状细胞病患儿脉搏血氧测量值的变化取决于初始氧饱和度测量值。
Variability of pulse oximetry measurement over 1 year in children with sickle cell disease depends on initial oxygen saturation measurement.
机构信息
Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
出版信息
Pediatr Blood Cancer. 2010 Jul 1;54(7):1017-9. doi: 10.1002/pbc.22420.
A prospective cohort of children with sickle cell disease (SCD) was evaluated to determine the variability of daytime pulse oximetry among three measurements over approximately 1 year. Fifty-eight participants were evaluated. Asymptomatic children with initial oxygen saturation < or = 92% had a mean range over 1 year of 4.6% (2.1-7.5%). In contrast, asymptomatic children whose oxygen saturation was >92% had a mean range of 1.9% (0-5.5%). These results suggest, changes in pulse oximetry measurement of approximately 5% may not be clinically significant in otherwise, healthy children with SCD with previous pulse oximetry < or = 92%.
一项前瞻性队列研究评估了患有镰状细胞病（SCD）的儿童，以确定大约 1 年内三次测量日间脉搏血氧饱和度的可变性。评估了 58 名参与者。初始血氧饱和度<或=92%的无症状儿童在 1 年内的平均范围为 4.6%（2.1-7.5%）。相比之下，血氧饱和度>92%的无症状儿童的平均范围为 1.9%（0-5.5%）。这些结果表明，在以前脉搏血氧饱和度<或=92%的情况下，无其他临床症状的 SCD 儿童，脉搏血氧饱和度测量值变化约 5%可能无临床意义。
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