Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Pediatr Blood Cancer. 2010 Jul 1;54(7):1017-9. doi: 10.1002/pbc.22420.
A prospective cohort of children with sickle cell disease (SCD) was evaluated to determine the variability of daytime pulse oximetry among three measurements over approximately 1 year. Fifty-eight participants were evaluated. Asymptomatic children with initial oxygen saturation < or = 92% had a mean range over 1 year of 4.6% (2.1-7.5%). In contrast, asymptomatic children whose oxygen saturation was >92% had a mean range of 1.9% (0-5.5%). These results suggest, changes in pulse oximetry measurement of approximately 5% may not be clinically significant in otherwise, healthy children with SCD with previous pulse oximetry < or = 92%.
一项前瞻性队列研究评估了患有镰状细胞病（SCD）的儿童，以确定大约 1 年内三次测量日间脉搏血氧饱和度的可变性。评估了 58 名参与者。初始血氧饱和度<或=92%的无症状儿童在 1 年内的平均范围为 4.6%（2.1-7.5%）。相比之下，血氧饱和度>92%的无症状儿童的平均范围为 1.9%（0-5.5%）。这些结果表明，在以前脉搏血氧饱和度<或=92%的情况下，无其他临床症状的 SCD 儿童，脉搏血氧饱和度测量值变化约 5%可能无临床意义。
