Weston Smith S G, Glass U H, Acharya J, Pearson T C
Division of Haematology, United Medical School, Guy's Hospital, St Thomas's Hospital, London.
Clin Lab Haematol. 1989;11(3):185-8. doi: 10.1111/j.1365-2257.1989.tb00207.x.
The place of pulse oximetry in monitoring arterial oxygen saturation in sickle cell disease has been evaluated. In four admissions of patients with sickle cell anaemia with varying degrees of arterial haemoglobin oxygen desaturation, pulse oximetry was compared with a simultaneous assessment of oxygen saturation by arterial blood gas measurement and oxygen dissociation curve (ODC) analysis. Close agreement was found between the oxygen saturation measured by pulse oximetry and that calculated from the measured arterial partial pressure of oxygen (PaO2) with reference to the patient's own ODC. Calculation of oxygen saturation by the blood gas analyser assuming a normal ODC was erroneous. Pulse oximetry is an accurate and effective non-invasive method for monitoring the arterial oxygen saturation in sickle cell disease.
已对脉搏血氧饱和度测定法在镰状细胞病动脉血氧饱和度监测中的作用进行了评估。在4例不同程度动脉血红蛋白氧去饱和的镰状细胞贫血患者入院期间，将脉搏血氧饱和度测定法与通过动脉血气测量和氧解离曲线（ODC）分析同时评估的血氧饱和度进行了比较。发现脉搏血氧饱和度测定法测得的血氧饱和度与根据测得的动脉血氧分压（PaO2）并参照患者自身ODC计算得出的血氧饱和度之间具有高度一致性。假设ODC正常，通过血气分析仪计算血氧饱和度是错误的。脉搏血氧饱和度测定法是监测镰状细胞病动脉血氧饱和度的一种准确有效的非侵入性方法。
