Kuznetsova Tatiana, Herbots Lieven, Jin Yu, Stolarz-Skrzypek Katarzyna, Staessen Jan A
Division of Hypertension and Cardiac Rehabilitation, Department of Cardiovascular Diseases, University of Leuven, Campus Sint Rafaël, Kapucijnenvoer 35, Block D, B-3000 Leuven, Belgium.
Expert Rev Cardiovasc Ther. 2010 Feb;8(2):251-8. doi: 10.1586/erc.10.3.
Because life expectancy and the prevalence of risk factors such as hypertension, obesity and diabetes are rising globally, heart failure (HF) is growing into a major health problem. Impairment of left ventricular (LV) diastolic function as well as systolic function appear very early in the course of heart disease. Recent HF guidelines, therefore, place special emphasis on the detection of subclinical LV dysfunction and the timely identification of risk factors for HF. Conventional echocardiography combined with new imaging techniques such as tissue Doppler and tissue tracking are sensitive tools to detect early subclinical deterioration of LV function. Community-based studies revealed a higher prevalence of LV systolic and diastolic dysfunction using the new echocardiographic imaging techniques. Future prospective studies will clarify the hitherto unknown prognosis associated with early symptom-free LV dysfunction.
由于全球预期寿命以及高血压、肥胖症和糖尿病等风险因素的患病率不断上升，心力衰竭（HF）正日益成为一个重大的健康问题。左心室（LV）舒张功能以及收缩功能的损害在心脏病病程中很早就会出现。因此，最新的心力衰竭指南特别强调亚临床左心室功能障碍的检测以及心力衰竭风险因素的及时识别。传统超声心动图结合组织多普勒和组织追踪等新成像技术是检测左心室功能早期亚临床恶化的敏感工具。基于社区的研究表明，使用新的超声心动图成像技术，左心室收缩和舒张功能障碍的患病率更高。未来的前瞻性研究将阐明迄今未知的与早期无症状左心室功能障碍相关的预后情况。
