Brehm A, Krimbas C B
Department of Genetics, Agricultural University of Athens, Greece.
J Hered. 1991 Mar-Apr;82(2):110-7. doi: 10.1093/oxfordjournals.jhered.a111044.
The inversion polymorphism of Drosophila obscura Fallen, a European species of the obscura group of the subgenus Sophophora, is described. A total of 21 inversions have been recorded; they are located in the five large chromosomes of the species (a dot chromosome is also present) and form 25 gene arrangements present in the species' natural populations. Strains from five different countries were studied. Two of these inversions were found to be pericentric, and the remaining were paracentric. The presence of "hot" points (multibreaks) was noticed. The distribution of the relative lengths of inversions conformed to the Van Valen-Levins distribution, contrary to what happens in D. subobscura. Observations also showed that there is no crossover inhibition between nonoverlapping inversions. The phylogeny of chromosome C was reconstructed; the existence of several arrangements not found was postulated; and the primitive gene arrangement, linking D. obscura to its closely related species was identified, as well as the primitive gene arrangements of the other chromosomes. Photographic maps of the chromosomes of D. obscura are provided here.
描述了果蝇属黑腹果蝇亚属暗果蝇组的一种欧洲物种——暗果蝇（Drosophila obscura Fallen）的倒位多态性。共记录到21种倒位；它们位于该物种的五条大染色体上（还存在一条点状染色体），并在该物种的自然种群中形成了25种基因排列。研究了来自五个不同国家的菌株。发现其中两种倒位是臂间倒位，其余的是臂内倒位。注意到存在“热点”（多重断裂）。倒位相对长度的分布符合范·瓦伦-莱文斯分布，这与在亚暗果蝇（D. subobscura）中发生的情况相反。观察还表明，非重叠倒位之间不存在交叉抑制。重建了染色体C的系统发育；推测存在几种未发现的排列；确定了将暗果蝇与其近缘物种联系起来的原始基因排列，以及其他染色体的原始基因排列。这里提供了暗果蝇染色体的照相图谱。
