Liu Mei-yan, Jiang Rong-huan, Hu Da-yi, Yu Xin, Fan Qian, Zheng Min-ru, Xu Li-gang
Cardiology Department, Peking University People's Hospital, Beijing 100044, China.
Zhonghua Xin Xue Guan Bing Za Zhi. 2009 Oct;37(10):904-7.
To compare the incidence of emotional disorder in patients with acute or stable coronary heart disease.
A total of 298 patients with suspected coronary heart disease (CHD) were designed into three groups based on of coronary angiography results: acute coronary syndrome (ACS, n = 128), stable angina pectoris (SAP, n = 108) and non-CHD (n = 62). All patients were evaluated by Zung Self-rating Depression Scale (SDS), Zung Self-rating Anxiety Scale(SAS) and Hamilton Depression Rating Scale (HRSD) for depression and anxiety before coronary angiography (CAG), 3 days after CAG, and 1 day before discharge.
Incidences of depression and anxiety were significantly higher the ACS group (65.6%and 78.9% before CAG; 60.9% and 70.3% 3 days post CAG; 45.3%and 64.8% before discharge) compared patients with SAP (18.5% and 26.9% before CAG; 17.6% and 28.7% 3 days post CAG; 15.7% and 26.9% before discharge, all P < 0.05 vs. ACS) and non-CHD patients (32.3% and 25.8% before CAG; 27.4% and 24.2% 3 days post CAG; 29.0% and 30.6% before discharge, all P < 0.05 vs. ACS) while the depression and anxiety incidences were similar between patients with SAP and non-CHD in this cohort (P > 0.05).
Emotional disorder is common in patients with suspected heart diseases, especially in patients with ACS. Psychological distress of patients with suspected heart disease should be evaluated and treated.
比较急性或稳定型冠心病患者情绪障碍的发生率。
根据冠状动脉造影结果,将298例疑似冠心病(CHD)患者分为三组:急性冠状动脉综合征(ACS,n = 128)、稳定型心绞痛(SAP,n = 108)和非冠心病组(n = 62)。所有患者在冠状动脉造影(CAG)前、CAG后3天及出院前1天,采用zung自评抑郁量表(SDS)、zung自评焦虑量表(SAS)和汉密尔顿抑郁量表(HRSD)评估抑郁和焦虑情况。
与SAP患者(CAG前18.5%和26.9%;CAG后3天17.6%和28.7%;出院前15.7%和26.9%,与ACS组相比所有P < 0.05)和非冠心病患者(CAG前32.3%和25.8%;CAG后3天27.4%和24.2%;出院前29.0%和30.6%,与ACS组相比所有P < 0.05)相比,ACS组抑郁和焦虑发生率显著更高,而该队列中SAP患者和非冠心病患者的抑郁和焦虑发生率相似(P > 0.05)。
情绪障碍在疑似心脏病患者中很常见,尤其是ACS患者。应评估和治疗疑似心脏病患者的心理困扰。