Department of Pediatrics C, Schneider Children's Medical Center of Israel, 14 Kaplan Street, Petah Tiqwa, Israel.
Int J Infect Dis. 2010 Sep;14 Suppl 3:e253-5. doi: 10.1016/j.ijid.2009.06.033. Epub 2010 Feb 6.
We describe the clinical course of a previously healthy 20-month-old toddler admitted with high fever and leukocytosis. Blood culture grew Streptococcus pneumoniae serotype 19A, belonging to the ST663 clone, highly resistant to penicillin, ceftriaxone, and erythromycin. The same clone with identical antibiogram was isolated from the nasopharynx of another three of the other five healthy children attending the same daycare center as the patient. This case exemplifies the potential problems posed by highly-resistant S. pneumoniae serotype 19A, an emerging pathogen worldwide.
我们描述了一例先前健康的 20 个月大的幼儿的临床病程，该幼儿因高热和白细胞增多入院。血培养生长出对青霉素、头孢曲松和红霉素高度耐药的 19A 型肺炎链球菌，该克隆属于 ST663 克隆，与患者同处一家日托中心的另外 5 名健康儿童中的另外 3 名的鼻咽部分离出了同样具有相同药敏谱的同一克隆。本病例说明了在全球范围内新兴病原体 19A 型高度耐药肺炎链球菌所带来的潜在问题。
