Department of Woman and Child, Division Woman, Fetal Medicine Unit, University Hospitals Leuven, Leuven, Belgium.
J Am Soc Echocardiogr. 2010 Mar;23(3):301-8. doi: 10.1016/j.echo.2009.12.024.
The aim of this study was to assess speckle tracking-derived fetal cardiac function in a normal population and in recipient fetuses of twin-to-twin transfusion syndrome (TTTS).
A case-control study was conducted of 59 uncomplicated singleton pregnancies and 17 recipient fetuses of TTTS. Peak systolic strain, strain rate, velocity, and displacement were calculated, corrected for gestational age, and compared between patients with TTTS and controls.
The feasibility of speckle tracking was 83% in controls but only 61% in patients with TTTS. Myocardial velocity and displacement increased over gestation, and regional differences were present within each wall and between walls. Strain and strain rate were stable within each wall but were higher in the right ventricle than in the left ventricle and septum. Right ventricular strain was decreased in patients with TTTS compared with controls (0.75+/-0.34 vs 1.00+/-0.37 multiples of the median, P=.04).
The feasibility of speckle tracking is low when imaging conditions are challenging, but it can identify right ventricular failure in selected patients with TTTS.
本研究旨在评估斑点追踪技术在正常人群和双胎输血综合征（TTTS）受血胎儿中的胎儿心脏功能。
对 59 例单纯单胎妊娠和 17 例 TTTS 受血胎儿进行病例对照研究。计算收缩期峰值应变、应变率、速度和位移，并校正胎龄，比较 TTTS 患者与对照组之间的差异。
在对照组中，斑点追踪的可行性为 83%，但在 TTTS 患者中仅为 61%。心肌速度和位移随妊娠而增加，并且在每个壁内和壁之间存在区域差异。应变和应变率在每个壁内是稳定的，但右心室高于左心室和室间隔。与对照组相比，TTTS 患者的右心室应变降低（0.75+/-0.34 与 1.00+/-0.37 中位数倍数，P=.04）。
当成像条件具有挑战性时，斑点追踪的可行性较低，但它可以识别选定的 TTTS 患者的右心室衰竭。
