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本文引用的文献

1
The role of mitogen-activated protein (MAP) kinase signalling components and the Ste12 transcription factor in germination and pathogenicity of Botrytis cinerea.丝裂原活化蛋白（MAP）激酶信号成分和 Ste12 转录因子在 Botrytis cinerea 萌发和致病性中的作用。
Mol Plant Pathol. 2010 Jan;11(1):105-19. doi: 10.1111/j.1364-3703.2009.00579.x.
2
fost12, the Fusarium oxysporum homolog of the transcription factor Ste12, is upregulated during plant infection and required for virulence.在植物感染过程中，Fusarium oxysporum 转录因子 Ste12 的同源物 fost12 被上调，并对毒性的形成是必需的。
Fungal Genet Biol. 2010 Mar;47(3):216-25. doi: 10.1016/j.fgb.2009.11.006. Epub 2009 Nov 23.
3
Fusarium oxysporum Ste12 controls invasive growth and virulence downstream of the Fmk1 MAPK cascade.尖孢镰刀菌Ste12在Fmk1丝裂原活化蛋白激酶级联反应下游控制侵入性生长和毒力。
Mol Plant Microbe Interact. 2009 Jul;22(7):830-9. doi: 10.1094/MPMI-22-7-0830.
4
Identification of novel virulence factors associated with signal transduction pathways in Alternaria brassicicola.与十字花科链格孢菌信号转导途径相关的新型毒力因子的鉴定
Mol Microbiol. 2009 Jun;72(6):1316-33. doi: 10.1111/j.1365-2958.2009.06689.x. Epub 2009 May 13.
5
An STE12 gene identified in the mycorrhizal fungus Glomus intraradices restores infectivity of a hemibiotrophic plant pathogen.在丛枝菌根真菌根内球囊霉中鉴定出的STE12基因可恢复半活体营养型植物病原体的感染力。
New Phytol. 2009;181(3):693-707. doi: 10.1111/j.1469-8137.2008.02696.x. Epub 2008 Dec 16.
6
The evolution of combinatorial gene regulation in fungi.真菌中组合基因调控的进化
PLoS Biol. 2008 Feb;6(2):e38. doi: 10.1371/journal.pbio.0060038.
7
Divergence of transcription factor binding sites across related yeast species.相关酵母物种间转录因子结合位点的差异
Science. 2007 Aug 10;317(5839):815-9. doi: 10.1126/science.1140748.
8
Regulation and role of a STE12-like transcription factor from the plant pathogen Colletotrichum lindemuthianum.植物病原菌林氏炭疽菌中一种STE12样转录因子的调控与作用
Mol Microbiol. 2007 Apr;64(1):68-82. doi: 10.1111/j.1365-2958.2007.05639.x.
9
Developmental regulation of an adhesin gene during cellular morphogenesis in the fungal pathogen Candida albicans.白色念珠菌这一真菌病原体在细胞形态发生过程中黏附素基因的发育调控。
Eukaryot Cell. 2007 Apr;6(4):682-92. doi: 10.1128/EC.00340-06. Epub 2007 Feb 2.
10
Function analysis of steA homolog in Aspergillus oryzae.米曲霉中steA同源物的功能分析
Fungal Genet Biol. 2007 May;44(5):330-8. doi: 10.1016/j.fgb.2006.10.009. Epub 2006 Dec 18.

Ste12及类Ste12蛋白，即调节发育和致病性的真菌转录因子。

Ste12 and Ste12-like proteins, fungal transcription factors regulating development and pathogenicity.

作者信息

Wong Sak Hoi Joanne, Dumas Bernard

机构信息

Université de Toulouse, UPS, Surfaces Cellulaires et Signalisation chez les Végétaux, Castanet-Tolosan, France.

出版信息

Eukaryot Cell. 2010 Apr;9(4):480-5. doi: 10.1128/EC.00333-09. Epub 2010 Feb 5.

DOI:10.1128/EC.00333-09
PMID:20139240
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2863410/
Abstract

Ste12 and Ste12-like proteins are transcription factors found exclusively in the fungal kingdom. In the yeast model Saccharomyces cerevisiae, where the first member was identified, Ste12p was shown to regulate mating and invasive/pseudohyphal growth. In recent literature, there have been several reports of Ste12-like factors in multiple fungal systems, yeasts or filamentous fungi, with saprophytic or parasitic life-styles. In all these models, Ste12 and Ste12-like factors are involved in the regulation of fungal development and pathogenicity. In this review, we discuss the features, the regulation, and the role of Ste12 and Ste12-like factors by highlighting the similarities and dissimilarities that occur within this group.

摘要

Ste12及类Ste12蛋白是仅在真菌界发现的转录因子。在首个成员被鉴定出的酵母模型酿酒酵母中，Ste12p被证明可调控交配及侵袭性/假菌丝生长。在最近的文献中，有几篇关于多种真菌系统（酵母或丝状真菌，具有腐生或寄生生活方式）中类Ste12因子的报道。在所有这些模型中，Ste12及类Ste12因子都参与真菌发育和致病性的调控。在本综述中，我们通过强调该组内出现的异同来讨论Ste12及类Ste12因子的特征、调控及作用。