Song Han-Jian, Li Xiao-Feng, Pei Xin-Ran, Sun Zhan-Bin, Pan Han-Xu
School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, China.
J Fungi (Basel). 2025 Mar 15;11(3):223. doi: 10.3390/jof11030223.
Transcription factors are extensively found in fungi and are involved in the regulation of multiple biological processes, including growth, development, conidiation, morphology, stresses tolerance, and virulence, as well as the production of secondary metabolites. Biocontrol is a complex biological process through which several biocontrol behaviors, such as the secretion of cell wall-degrading enzymes and the production of secondary metabolites, are regulated by transcription factors. To date, biocontrol-related transcription factors have been reported in several biocontrol fungi, such as , , , and different species in the genera , , and . However, comprehensive reviews summarizing and analyzing transcription factors with biocontrol potential in these fungi are scarce. This review begins by giving a basic overview of transcription factors and their functions. Then, the role of biocontrol-related transcription factors in biocontrol fungi is discussed. Lastly, possible approaches for further work on transcription factors in biocontrol fungi are suggested. This review provides a basis for further elaborating the molecular mechanisms of transcription factors in the context of biocontrol.
转录因子在真菌中广泛存在，参与多种生物学过程的调控，包括生长、发育、产孢、形态、胁迫耐受性和毒力，以及次级代谢产物的产生。生物防治是一个复杂的生物学过程，转录因子可调控多种生物防治行为，如细胞壁降解酶的分泌和次级代谢产物的产生。迄今为止，已在几种生防真菌中报道了与生物防治相关的转录因子，如[具体真菌名称1]、[具体真菌名称2]、[具体真菌名称3]以及[具体属名1]、[具体属名2]和[具体属名3]中的不同物种。然而，缺乏对这些真菌中具有生物防治潜力的转录因子进行总结和分析的全面综述。本综述首先对转录因子及其功能进行基本概述。然后，讨论与生物防治相关的转录因子在生防真菌中的作用。最后，提出了在生防真菌中转录因子进一步研究的可能方法。本综述为在生物防治背景下进一步阐述转录因子的分子机制提供了基础。
