Department of Neurology, Faculty of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran.
Neurol India. 2009 Nov-Dec;57(6):768-71. doi: 10.4103/0028-3886.59474.
One of the prominent disturbances in Parkinson's disease (PD) is bradykinesia. We studied performance of hand-to-mouth reach reaction time (RT) in right-handed PD patients and nine age and sex matched healthy control subjects. Participants practiced hand-to-mouth reach skill in response to a visual stimulus, 120 times a day for a period of one week. Using Kinemetrix 3D Motion Analysis system, the effects of motor skill practice and learning retention were investigated. Pretest performance was compared with performances on the second and seventh day of the study, and also performance on fourteenth day with no further practice for one week. There was a significant reduction in the mean RT in the control group after one week of practice. In PD patients the reduction in the mean RT was significant between pretest and first test sessions (P < 0.01). However, the difference was not significant between the first and second session (P = 0.06) and also between the second and third test sessions (P = 1.0). Short-term practice can improve bradykinesia in patients with PD but it is not long-lasting.
帕金森病（PD）的一个突出障碍是运动迟缓。我们研究了右手 PD 患者和 9 名年龄和性别匹配的健康对照者的手到口到达反应时间（RT）的表现。参与者每天练习 120 次，以视觉刺激作为回应，持续一周。使用 Kinemetrix 3D 运动分析系统，研究了运动技能练习和学习保持的效果。将预测试性能与研究的第二天和第七天的性能进行比较，并且在没有进一步练习的一周后，将第十四天的性能与没有进一步练习的一周进行比较。经过一周的练习，对照组的平均 RT 明显降低。在 PD 患者中，在预测试和第一次测试之间的平均 RT 显著降低（P < 0.01）。但是，第一次和第二次测试之间（P = 0.06）和第二次和第三次测试之间（P = 1.0）的差异并不显著。短期练习可以改善 PD 患者的运动迟缓，但效果不持久。
