Rohmiller Michael T, Akbarnia Behrooz A, Raiszadeh Kian, Raiszadeh Kamshad, Canale Sarah
From the *Cincinnati Spine Institute, Cincinnati, OH; †Department of Orthopedics, University of California, San Diego, CA; ‡San Diego Center for Spinal Disorders, La Jolla, CA; §Kaiser Permanente, San Diego, CA; and ¶La Jolla Spine Institute, La Jolla, CA.
Spine (Phila Pa 1976). 2010 Mar 15;35(6):642-6. doi: 10.1097/BRS.0b013e3181b616eb.
Retrospective review of clinical cases.
This study describes the success rate of closed suction irrigation system (CSIS) in the treatment of post operative spinal infections.
Given the widening use of spinal instrumentation, the management of related postoperative deep wound infections has become increasingly important. In the literature, there have been reports of several treatment methods yet no firmly established protocol for management of postoperative deep wound infections exists. The goal of this study was to determine the effectiveness of our protocol employing (CSIS) in the treatment of postoperative deep wound infections.
A retrospective record review of 500 posterior instrumented fusions between 1990 and 2002. Twenty-eight consecutive infections (5%) were diagnosed and treated by a standardized treatment protocol of Incision and Drainage, and CSIS. Cultures were obtained, wounds closed primarily, and appropriate intravenous antibiotic treatments initiated. For statistical evaluation, patients were assigned a risk factor (RF) described by Levi et al (J Neurosurg. 1997;86:975-980). Point values were assigned to medical comorbidities that may contribute to postoperative infection risk; higher RF values indicate an increased risk.
Twenty-one acute and 7 late (>6 months) infections were followed for 22.3 months (1-86 months), post-CSIS treatment. Twenty-one (75%) resolved without recurrence with one CSIS treatment. Seven acute infections (25%) required a second course of treatment. Hospitalization for the index procedure averaged 15.4 days; 28.9 days for reinfections. No patient with an acute infection required implant removal. The reinfection group had higher blood loss, more levels fused, and longer hospitalization. The reinfection group was comprised entirely of pediatric patients.
No correlation was found between RF values and greater risk of recurrent infection. Removal of implants is unnecessary in acute infections, provided the infection does not return. CSIS is an effective method for treatment of postoperative wound infections following instrumented spinal fusion avoiding the need for secondary closure.
临床病例回顾性研究。
本研究描述封闭式吸引冲洗系统(CSIS)治疗术后脊柱感染的成功率。
鉴于脊柱内固定器械使用的增加,相关术后深部伤口感染的管理变得越发重要。文献中已有多种治疗方法的报道,但尚无已确立的术后深部伤口感染管理方案。本研究的目的是确定我们采用CSIS的方案治疗术后深部伤口感染的有效性。
对1990年至2002年间500例后路器械辅助融合术进行回顾性记录分析。连续28例感染(5%)通过切开引流和CSIS的标准化治疗方案进行诊断和治疗。获取培养物,伤口一期缝合,并开始适当的静脉抗生素治疗。为进行统计学评估,为患者指定了Levi等人(《神经外科学杂志》。1997年;86:975 - 980)描述的风险因素(RF)。为可能导致术后感染风险的内科合并症指定分值;RF值越高表明风险增加。
21例急性感染和7例晚期(>6个月)感染在CSIS治疗后随访22.3个月(1 - 86个月)。21例(75%)经一次CSIS治疗后痊愈且无复发。7例急性感染(25%)需要第二个疗程的治疗。初次手术的平均住院时间为15.4天;再次感染的住院时间为28.9天。急性感染患者均无需取出植入物。再次感染组失血更多,融合节段更多,住院时间更长。再次感染组全部为儿科患者。
未发现RF值与复发性感染风险增加之间存在相关性。急性感染时,只要感染不再复发,无需取出植入物。CSIS是治疗器械辅助脊柱融合术后伤口感染的有效方法,可避免二次缝合。