Department of Spine Surgery, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
J Orthop Surg Res. 2021 Jul 9;16(1):445. doi: 10.1186/s13018-021-02588-y.
Previous reports concerning deep surgical site infection (SSI) after posterior spinal instrumentation treated with vacuum-assisted closure (VAC) system indicated that most patients must suffer from a delayed incision suture. To date, there are no published reports about the application of incisional VAC following a one-stage incision suture in the treatment of spinal infections. The purpose of this study was to evaluate the feasibility and efficacy of using an incisional VAC system following a one-stage incision suture combined with continuous irrigation to treat early deep SSI after posterior lumbar fusion with instrumentation.
Twenty-one patients who were identified as early deep SSI after posterior lumbar fusion with instrumentation were treated by incisional VAC following a one-stage incision suture combined with continuous irrigation at our spine surgery center between January 2014 and March 2020. Detailed data from medical records were collected and analyzed, including age, gender, primary diagnosis, original operation, number of VAC dressing changes, duration of continuous irrigation, hospital stay, risk factors for infection, bacteria type, and laboratory data. Clinical efficacy was assessed using the pre- and postoperative visual analog scale (VAS) for back pain and Kirkaldy-Willis functional criteria by regular follow-up.
All the patients were cured and retained implants with an average of 1.9 times of VAC dressing replacement, and an average of 10.2 days of continuous irrigation. There were significant differences between pre-operation and post-operation in ESR, CRP, and VAS score of back pain, respectively (P < 0.05). The satisfactory rate was 90.5% according to Kirkaldy-Willis functional criteria. One patient developed a back skin rash with itching around the wound because of long-time contact with the VAC dressing. There was no recurrent infection or other complications during follow-up.
Our preliminary results support that the treatment protocol is feasible and effective to treat early deep SSI following posterior lumbar fusion with instrumentation.
既往有关后路脊柱内固定术后应用真空辅助闭合(VAC)系统治疗深部手术部位感染(SSI)的报道表明,大多数患者必须延迟切口缝合。迄今为止,尚无关于一期缝合切口后应用切口 VAC 治疗脊柱感染的报道。本研究旨在评估一期缝合切口后应用切口 VAC 联合持续冲洗治疗后路腰椎融合内固定术后早期深部 SSI 的可行性和疗效。
2014 年 1 月至 2020 年 3 月,我们脊柱外科中心采用一期缝合切口后应用切口 VAC 联合持续冲洗治疗后路腰椎融合内固定术后早期深部 SSI 的 21 例患者。收集并分析了病历中的详细数据,包括年龄、性别、主要诊断、原手术、VAC 更换次数、持续冲洗时间、住院时间、感染危险因素、细菌类型和实验室数据。通过定期随访,采用术前和术后的视觉模拟评分(VAS)评估腰痛和 Kirkaldy-Willis 功能标准评估临床疗效。
所有患者均治愈,保留了植入物,VAC 更换次数平均为 1.9 次,持续冲洗时间平均为 10.2 天。ESR、CRP 和 VAS 评分分别在术前和术后有显著差异(P<0.05)。根据 Kirkaldy-Willis 功能标准,满意度为 90.5%。1 例患者因长时间接触 VAC 敷料,伤口周围出现背部皮肤皮疹伴瘙痒。随访期间无复发性感染或其他并发症。
我们的初步结果支持该治疗方案治疗后路腰椎融合内固定术后早期深部 SSI 是可行和有效的。