Otorhinolaryngology Unit, IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Acta Otorhinolaryngol Ital. 2009 Jun;29(3):164-8.
Esthesioneuroblastoma is a rare tumour, for which a multimodal approach, including a combination of surgery and radiation, appears to provide the best disease-free and overall survival. Well-known for its tendency for local recurrence and distant spreading by both lymphatic and haematogenous routes, the most common sites of metastases are lungs and bones, followed by liver, spleen, scalp, breast, adrenals and ovary. One single case of metastasis to the trachea has been reported in the literature. The case is reported here of a patient who developed metastatic esthesioneuroblastoma to the trachea 18 months after primary surgery and radiation therapy. The patient was treated by two subsequent N-YAG laser endoscopic resections and chemotherapy.
嗅神经母细胞瘤是一种罕见的肿瘤，采用包括手术和放疗在内的多模态方法似乎可以提供最佳的无疾病和总体生存率。它以局部复发和通过淋巴和血行途径远处播散为特征，最常见的转移部位是肺和骨骼，其次是肝、脾、头皮、乳腺、肾上腺和卵巢。文献中仅报道过一例转移至气管的病例。本文报告了 18 个月前接受原发性手术和放疗后发生气管转移性嗅神经母细胞瘤的患者。该患者接受了两次后续的 N-YAG 激光内镜切除术和化疗。
