Khosla Manraj, Pecci Cristina, Do Annie, McGhan Lee, Seetharam Mahesh, Sue Richard
Department of Internal Medicine, 500 W. Thomas Rd., Suite 900, Phoenix, AZ 85013, USA.
Ear Nose Throat J. 2018 Apr-May;97(4-5):E18-E21.
Esthesioneuroblastoma (ENB) is an uncommon sinonasal tract tumor, and it is even more uncommon among all neoplasms. Literature regarding the incidence and spread of the disease is limited. The prognosis of metastatic disease is poor. In this report, we present a case of recurrent ENB in a young woman involving metastasis to the neck, lungs, and ovary. Metastasis to the cervical lymph nodes is relatively common, but metastasis to the lungs is rare. Furthermore, to our knowledge, no cases of ovarian metastases of ENB have been reported. This case highlights the potential for widespread metastatic disease, suggesting the need for more frequent and thorough surveillance of patients diagnosed with recurrences of this tumor.
嗅神经母细胞瘤（ENB）是一种罕见的鼻窦肿瘤，在所有肿瘤中更为罕见。关于该疾病发病率和扩散的文献有限。转移性疾病的预后很差。在本报告中，我们介绍了一名年轻女性复发性ENB的病例，该病例涉及颈部、肺部和卵巢转移。转移至颈部淋巴结相对常见，但转移至肺部则较为罕见。此外，据我们所知，尚未有ENB发生卵巢转移的病例报道。该病例突出了广泛转移性疾病的可能性，提示对于诊断为该肿瘤复发的患者需要更频繁、更全面的监测。
