Program in Pathology of Health Sciences, Federal University of Porto Alegre, Rua Sarmento Leite 245/204, Porto Alegre, RS, Brazil.
Braz J Infect Dis. 2009 Apr;13(2):123-4. doi: 10.1590/s1413-86702009000200010.
Enterococci are part of the endogenous flora of human beings, are naturally resistant to several classes of antimicrobials, and are able to acquire resistance with relative ease. Currently the vancomycin-resistant enterococci are spread all over the world and treatment options for infections caused by it are often extremely limited. We assessed 193 vancomycin-resistant Enterococcus faecalis isolates collected from four different hospitals in Porto Alegre for their susceptibility to fosfomycin using the E-test and agar diffusion. Fosfomycin proved to be active in vitro against the great majority of isolates, indicating that it is a valid option in the treatment of these infections.
肠球菌是人类内源性菌群的一部分，天然对抗几种类别的抗生素，并且相对容易获得耐药性。目前，耐万古霉素肠球菌已经在全球范围内传播，其引起的感染的治疗选择往往极其有限。我们使用 E 试验和琼脂扩散法评估了来自阿雷格里港的 4 家不同医院的 193 株耐万古霉素粪肠球菌分离株对磷霉素的敏感性。磷霉素在体外对绝大多数分离株均显示出活性，表明其是治疗这些感染的有效选择。
