University of Malaya, Centre of Excellence for Research in AIDS, Malaya, Malaysia.
Am J Drug Alcohol Abuse. 2010 Jan;36(1):31-8. doi: 10.3109/00952990903544828.
To examine the association between HIV infection and psychiatric disorders among prisoners, where mental illness, substance abuse, and HIV are disproportionately represented.
Cross-sectional study.
Using a sequential randomization scheme, 200 HIV-seropositive and 200 HIV-seronegative prisoners were selected for evaluation of psychiatric illnesses with the Structured Clinical Interview for Diagnostic Statistical Manual of Mental Disorders-IV (SCID-I).
The prevalence of mental illness and substance use disorders, particularly opioid dependence, was extremely high. HIV infection was significantly correlated with age, ethnicity, marital status, history of injection drug use, lifetime duration of incarceration, substance abuse, and polysubstance drug use. After controlling for potential confounders, HIV infection was significantly associated with non-substance-induced psychiatric disorders (AOR = 1.92; 95% CI: 1.03-3.59). While prisoners with a triple diagnosis (psychiatric disorders, substance use disorders, and HIV) spent 46.7 more cumulative lifetime months in prison than those with only a psychiatric diagnosis (p < .01), those with a dual diagnosis (psychiatric plus substance use disorders) were comparable to those with one psychiatric diagnosis only. Neither HIV infection nor triple diagnosis was associated with violent offenses.
These findings suggest that a public health approach that simultaneously addresses psychiatric illnesses, substance abuse, and HIV infection is needed in both the correctional and the community settings in order to provide adequate care for triply-diagnosed patients and prevent them from returning to prison.
探讨囚犯中 HIV 感染与精神障碍之间的关联,因为在囚犯中,精神疾病、药物滥用和 HIV 的发病率不成比例。
横断面研究。
采用序贯随机抽样方案,选择 200 例 HIV 血清阳性和 200 例 HIV 血清阴性囚犯,使用《精神障碍诊断与统计手册-IV 版结构临床访谈》(SCID-I)评估精神疾病。
精神疾病和药物使用障碍,特别是阿片类药物依赖的患病率极高。HIV 感染与年龄、种族、婚姻状况、注射毒品使用史、终生监禁时间、药物滥用和多种药物滥用显著相关。在控制潜在混杂因素后,HIV 感染与非物质引起的精神障碍显著相关(AOR = 1.92;95%CI:1.03-3.59)。虽然同时患有精神障碍、物质使用障碍和 HIV 的囚犯比仅有精神障碍的囚犯累计入狱时间多 46.7 个月(p <.01),但同时患有双重诊断(精神障碍加物质使用障碍)的囚犯与仅有精神障碍的囚犯相似。HIV 感染或三重诊断均与暴力犯罪无关。
这些发现表明,需要在监狱和社区环境中采取公共卫生措施,同时解决精神疾病、药物滥用和 HIV 感染问题,以便为三重诊断患者提供充分的护理,防止他们重返监狱。