脑脊液中血液分化中的含铁小体。

Siderophages in differentiation of blood in cerebrospinal fluid.

作者信息

Veuger A J, Kortbeek L H, Booij A C

出版信息

Clin Neurol Neurosurg. 1977;80(1):46-56. doi: 10.1016/s0303-8467(78)80006-7.

PMID:201417

Abstract

This paper evaluates demonstration of siderophages as a method of differentiating blood in CSF. Of 1147 CSF samples, 125 were selected which had been obtained by lumbar puncture from patients with proven intracranial haemorrhage (spontaneous or traumatic) after an exactly known interval since the onset of clinical phenomena (haemorrhage or accident). No siderophages were found within 24 hours; in a few cases they were found on the second or the third day, and after that time they were found in the majority of cases. This is a pathognomonic finding. Collection of CSF in successive portions, qualification of the tap by the clinician as 'traumatic' or 'atraumatic', and demonstration of crenated red cells, were found to be unreliable methods. A modified apparatus for sedimentation is described.

摘要

本文评估了将含铁小体作为鉴别脑脊液中血液的一种方法。在1147份脑脊液样本中，选取了125份，这些样本是通过腰椎穿刺从已证实有颅内出血（自发性或外伤性）的患者中获取的，自临床症状（出血或事故）出现后经过了确切已知的时间间隔。在24小时内未发现含铁小体；少数情况下在第二天或第三天发现，此后在大多数病例中都能发现。这是一项具有诊断意义的发现。连续采集脑脊液、临床医生对穿刺定性为“外伤性”或“非外伤性”以及出现皱缩红细胞，这些方法被发现并不可靠。本文描述了一种改良的沉降装置。