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[重度抑郁症与成瘾问题]

[Severe depression and addictions].

作者信息

Cottencin O

机构信息

PU-PH. Faculté de Médecine de Lille, CHRU de Lille. Service d'Addictologie.

出版信息

Encephale. 2009 Dec;35 Suppl 7:S264-8. doi: 10.1016/S0013-7006(09)73483-9.

Abstract

Addictive co-morbidities (or co-occurrent disorder, double diagnosis, associated diagnosis) associated with depression are diagnoses which must be made independently and not only seen as a cluster as symptoms of the disorder or as disorders induced by taking the toxin. The association of an addictive disorder with depression raises a prognostic problem as this association results not only in mutual worsening of the two disorders but in a further problem of penalising access to care with an important sub-diagnosis. This is a common association ; however as 30 to 50% of patients admitted to psychiatric units in Europe have a mental disorder combined with substance abuse (alcohol, sedatives, cannabis). In this article we describe the different findings reported in the literature showing how this association is strong and may have consequences in terms of delayed diagnosis and prognostic and therapeutic impact. We also show that regardless of the origin of the association (attempted self-medication, addiction-induced depression, consequence of depression or a fortuitous association), dual psychiatric and addiction medicine practice is always justified even if this is frequently complex because of the ways in which the different facilities available to us operate in isolation.

摘要

与抑郁症相关的成瘾共病(或共现障碍、双重诊断、相关诊断)是必须独立做出的诊断,而不仅仅被视为该疾病的一组症状或因摄入毒素所致的疾病。成瘾性障碍与抑郁症的关联引发了一个预后问题,因为这种关联不仅会导致两种疾病相互恶化,还会带来另一个问题,即一个重要的子诊断会影响患者获得治疗的机会。这是一种常见的关联;然而,在欧洲,30%至50%入住精神科病房的患者患有精神障碍并伴有药物滥用(酒精、镇静剂、大麻)。在本文中,我们描述了文献中报道的不同研究结果,展示了这种关联有多紧密,以及它在延迟诊断、预后和治疗影响方面可能产生的后果。我们还表明,无论这种关联的根源是什么(自我治疗尝试、成瘾导致的抑郁症、抑郁症的后果或偶然关联),精神科和成瘾医学的联合诊疗总是合理的,即便由于我们现有的不同医疗设施各自独立运作的方式,这种联合诊疗常常很复杂。

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