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细尾半蝎蜇伤后发生的溶血性尿毒症综合征。

Hemolytic uremic syndrome following Hemiscorpius lepturus (scorpion) sting.

作者信息

Valavi E, Ansari M J Alemzadeh

机构信息

Department of Nephrology, Abuzar Pediatric Hospital, Ahwaz, Iran.

出版信息

Indian J Nephrol. 2008 Oct;18(4):166-8. doi: 10.4103/0971-4065.45293.

Abstract

Scorpion envenomations are a public health problem in many countries. Scorpions are second only to snakes in causing human fatalities from envenomation. Species of scorpions capable of inflicting fatal stings are living in North and South Africa, the Middle East, India, America, Trinidad, and Tobago. Hemiscorpius lepturus (from the Hemiscorpiidae family) is the most medically important scorpion in Iran which accounts for 92% of all hospitalized scorpion sting cases. The venom from H. lepturus is primarily a cytotoxic agent and has hemolytic, nephrotoxic, and to some extent, hepatotoxic activities. We found a combination of microangiopatic hemolytic anemia, thrombocytopenia, and acute renal failure in a seven year-old female child who was referred to us with a 12 h history of bloody urine following a H. lepturus sting. Her blood smear showed fragmented erythrocytes and burr cells, leading us to a diagnosis of hemolytic uremic syndrome (HUS). This report highlights the importance of acceptable prophylaxis and therapeutic protocols for HUS in these patients.

摘要

蝎子蜇伤在许多国家都是一个公共卫生问题。在因毒液导致人类死亡方面,蝎子仅次于蛇。能够致人死亡的蝎子种类分布在非洲北部和南部、中东、印度、美洲、特立尼达和多巴哥。细尾半蝎(属于半蝎科)是伊朗在医学上最重要的蝎子,占所有住院蝎子蜇伤病例的92%。细尾半蝎的毒液主要是一种细胞毒性剂,具有溶血、肾毒性,在一定程度上还具有肝毒性。我们发现一名7岁女童在被细尾半蝎蜇伤12小时后出现血尿,前来就诊时出现了微血管病性溶血性贫血、血小板减少和急性肾衰竭的组合症状。她的血涂片显示有破碎红细胞和棘状细胞,这使我们诊断为溶血尿毒综合征(HUS)。本报告强调了针对这些患者制定可接受的HUS预防和治疗方案的重要性。

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