Ozkan Ozcan, Alcigir Mehmet Eray
Çankırı Karatekin University, Çankırı, Turkey.
Department of Pathology, Kirikkale University, Faculty of Veterinary Medicine, Kirikkale, Turkey.
J Arthropod Borne Dis. 2019 Mar 30;13(1):104-115. eCollection 2019 Mar.
The aim of study was to compare macroscopical and histopathological findings between venoms belonging to two scorpion species, , and the newly discovered .
The animals used in this experimental study were fifteen New Zealand bred rabbits. Three groups were constituted as group I ( group, n= 6), group II ( group, n= 6) and group III (control group, n= 3). The animals in the group and the group were envenomed through an intravenous route. The rabbits were monitored for the first 24h following the envenomation. The animals dead within that time period were examined and all animals were sacrificed and standard necropsy process was performed at 24h.
The pathomorphological findings from group I were found to be more severe than those observed in group II. The venom from the newly identified has a greater effect than the venom from the Moreover, as this was a rabbit modeling study, the might pose the most serious health threat to infants in particular due to their smaller body weight.
These findings will provide a better understanding of envenomation of human beings in terms of the possible consequences of scorpion toxication on the organs.
本研究的目的是比较两种蝎子毒液以及新发现的蝎子毒液在宏观和组织病理学上的发现。
本实验研究使用了15只新西兰繁殖的兔子。分为三组:第一组([蝎子种类1]组,n = 6),第二组([蝎子种类2]组,n = 6)和第三组(对照组,n = 3)。[蝎子种类1]组和[蝎子种类2]组的动物通过静脉途径注射毒液。在注射毒液后的前24小时对兔子进行监测。对在该时间段内死亡的动物进行检查,并在24小时时对所有动物实施安乐死并进行标准尸检程序。
发现第一组的病理形态学发现比第二组更严重。新鉴定的[蝎子种类2]的毒液比[蝎子种类1]的毒液具有更大的作用。此外,由于这是一项兔子模型研究,[蝎子种类2]可能因其体重较小而对婴儿构成最严重的健康威胁。
这些发现将有助于更好地了解蝎子中毒对人体器官可能造成的后果。