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一名患有抗凝血酶III缺乏症的4岁女孩成功接受了肺动脉血栓切除术。

Successful pulmonary embolectomy in a 4-year-old girl with antithrombin III deficiency.

作者信息

Jean Nolwenn, Labombarda Fabien, De La Gastine Geoffroy, Raisky Olivier, Boudjemline Younes

机构信息

Department of Pediatrics, CHU Cote de Nacre, Caen, France.

出版信息

Pediatr Cardiol. 2010 Jul;31(5):711-3. doi: 10.1007/s00246-010-9653-5. Epub 2010 Feb 9.

DOI:10.1007/s00246-010-9653-5
PMID:20143056
Abstract

We report the case of a 4-year-old girl, successfully treated by surgical pulmonary embolectomy for acute massive pulmonary embolism. She was known to have a congenital antithrombin III deficiency diagnosed after a familial history of thromboembolic events. Surgical embolectomy may be considered as a treatment option in selected patient with anatomically extensive pulmonary embolism.

摘要

我们报告了一例4岁女孩的病例，她因急性大面积肺栓塞接受了外科肺动脉血栓切除术，治疗成功。她因有血栓栓塞事件家族史，被诊断为先天性抗凝血酶III缺乏症。对于解剖学上广泛的肺栓塞患者，外科血栓切除术可被视为一种治疗选择。

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Successful pulmonary embolectomy in a 4-year-old girl with antithrombin III deficiency.一名患有抗凝血酶III缺乏症的4岁女孩成功接受了肺动脉血栓切除术。
Pediatr Cardiol. 2010 Jul;31(5):711-3. doi: 10.1007/s00246-010-9653-5. Epub 2010 Feb 9.
2
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本文引用的文献

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Impact of inherited thrombophilia on venous thromboembolism in children: a systematic review and meta-analysis of observational studies.遗传性血栓形成倾向对儿童静脉血栓栓塞的影响：观察性研究的系统评价和荟萃分析
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Eur Heart J. 2008 Sep;29(18):2276-315. doi: 10.1093/eurheartj/ehn310. Epub 2008 Aug 30.
3
Thrombophilia in children with venous thromboembolic disease.
患有静脉血栓栓塞性疾病儿童的血栓形成倾向
Thromb Res. 2006;118(1):59-65. doi: 10.1016/j.thromres.2005.05.026. Epub 2005 Jul 1.
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Acute pulmonary embolism in childhood.儿童急性肺栓塞
Thromb Res. 2006;118(1):13-25. doi: 10.1016/j.thromres.2005.05.013. Epub 2005 Jun 29.
5
Incidence of venous thromboembolism in infants and children: data from the National Hospital Discharge Survey.婴幼儿静脉血栓栓塞症的发病率：来自国家医院出院调查的数据。
J Pediatr. 2004 Oct;145(4):563-5. doi: 10.1016/j.jpeds.2004.06.021.
6
Open pulmonary embolectomy for treatment of major pulmonary embolism.开胸肺动脉血栓切除术治疗大面积肺栓塞
Ann Thorac Surg. 2004 Mar;77(3):819-23; discussion 823. doi: 10.1016/j.athoracsur.2003.08.008.
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Acute pulmonary embolectomy: a contemporary approach.
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Arch Pediatr. 2000 Aug;7(8):851-4. doi: 10.1016/s0929-693x(00)80196-7.
9
Patent foramen ovale is an important predictor of adverse outcome in patients with major pulmonary embolism.卵圆孔未闭是主要肺栓塞患者不良预后的重要预测指标。
Circulation. 1998 May 19;97(19):1946-51. doi: 10.1161/01.cir.97.19.1946.
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Pulmonary embolism in children.儿童肺栓塞
Pediatr Clin North Am. 1994 Jun;41(3):569-84. doi: 10.1016/s0031-3955(16)38770-3.