Yalamanchili Kiran, Fleisher Arlen G, Lehrman Stuart G, Axelrod Howard I, Lafaro Rocco J, Sarabu Mohan R, Zias Elias A, Moggio Richard A
Internal Medicine, Westchester Medical Center/New York Medical College, Valhalla, New York, USA.
Ann Thorac Surg. 2004 Mar;77(3):819-23; discussion 823. doi: 10.1016/j.athoracsur.2003.08.008.
Inadequate data exist regarding the management of acute major pulmonary embolism. Various modalities that are used, including thrombolytics and embolectomy, have not been shown to conclusively improve mortality when compared to heparin. In the past, open pulmonary embolectomy was reserved for patients with severe hemodynamic instability because of its high mortality rate. Our objective was to analyze our experience with early embolectomy as an alternative for the treatment of major pulmonary embolism.
A retrospective review of charts of all patients undergoing pulmonary embolectomy at our institution over the last two years was performed. Patients were followed until their discharge from hospital.
There were 13 patients (7 women and 6 men). Four had massive and 9 had submassive pulmonary embolism. There was one mortality. Postoperative echocardiography showed no evidence of pulmonary hypertension in 7.
Open pulmonary embolectomy can be performed in patients with major pulmonary embolism with minimal mortality and morbidity. It may prevent the development of chronic thromboembolic pulmonary hypertension and should be a part of the algorithm in the treatment of major pulmonary embolism.
关于急性大面积肺栓塞的治疗,现有数据不足。所采用的各种治疗方式,包括溶栓治疗和栓子切除术,与肝素相比,尚未被证明能确凿地降低死亡率。过去,由于开放性肺栓子切除术死亡率高,仅用于严重血流动力学不稳定的患者。我们的目的是分析我们将早期栓子切除术作为大面积肺栓塞治疗替代方法的经验。
对过去两年在我院接受肺栓子切除术的所有患者的病历进行回顾性分析。对患者进行随访直至出院。
共13例患者(7例女性,6例男性)。4例为大面积肺栓塞,9例为次大面积肺栓塞。死亡1例。术后超声心动图显示7例无肺动脉高压迹象。
开放性肺栓子切除术可用于大面积肺栓塞患者,死亡率和发病率极低。它可能预防慢性血栓栓塞性肺动脉高压的发生,应成为大面积肺栓塞治疗方案的一部分。