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自体游离非血管化腓骨移植治疗桡骨远端骨巨细胞瘤。

Autogenous non-vascularized fibula for treatment of giant cell tumor of distal end radius.

机构信息

Department of Orthopaedics, UCMS and GTB Hospital, Delhi, India.

出版信息

Arch Orthop Trauma Surg. 2010 Dec;130(12):1467-73. doi: 10.1007/s00402-010-1059-6. Epub 2010 Feb 9.

Abstract

INTRODUCTION

Giant cell tumor of distal end of radius is treated by wide resection and intralesional procedures with former having better results. The various modalities for the defect created are vascularized/non-vascularized bone graft, osteoarticular allografts and custom-made prosthesis. We report outcome of wide resection and non-vascularized fibular grafting in biopsy-proven giant cell tumors.

PATIENTS AND METHODS

Nine patients with mean age of 40 years with Campanacci grade II giant cell tumor of distal radius were managed with radical excision of the tumor and reconstruction with ipsilateral free fibular graft.

RESULTS

Mean follow-up time was 56 months. One patient developed recurrence and was treated by amputation. All other patients showed a good union at fibular graft-radius junction. In wrist, average range of motion achieved at last follow-up was 40° of dorsiflexion, 30° of palmar flexion, 45° each of supination and pronation. Major complications encountered included graft fracture (2), wrist subluxation (2), tourniquet palsy (1), aseptic graft resorption (1) and tumor recurrence (1).

CONCLUSION

Reconstruction after wide excision by non-vascularized fibular graft is a viable alternative for giant cell tumors of the lower end of radius though it is a challenging procedure and may be accompanied by major complications.

摘要

介绍

桡骨远端的巨细胞瘤采用广泛切除和瘤内手术治疗,前者效果更好。对于所造成的缺损,有各种方法可供选择,包括带血管/不带血管的骨移植物、骨关节同种异体移植物和定制假体。我们报告经活检证实的巨细胞瘤采用广泛切除和非血管化腓骨移植的结果。

患者和方法

9 名平均年龄为 40 岁的患者患有桡骨远端 Campanacci 分级 II 级的巨细胞瘤,采用肿瘤根治性切除和同侧游离腓骨移植进行重建。

结果

平均随访时间为 56 个月。1 例患者复发,行截肢治疗。所有其他患者在腓骨移植物-桡骨交界处均有良好的愈合。在腕关节,末次随访时平均背屈活动度为 40°,掌屈 30°,旋前和旋后各 45°。主要并发症包括移植物骨折(2 例)、腕关节半脱位(2 例)、止血带麻痹(1 例)、无菌性移植物吸收(1 例)和肿瘤复发(1 例)。

结论

非血管化腓骨移植广泛切除后的重建是桡骨下端巨细胞瘤的一种可行替代方法,尽管这是一个具有挑战性的手术,可能伴有严重并发症。

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