Liu Siyi, Tao Shengxiang, Tan Jinhai, Hu Xiang, Liu Huiyi, Li Zonghuan
Department of Orthopedics, Zhongnan Hospital of Wuhan University, Wuchang District, Wuhan City.
Department of Surgery, 3rd Hospital of Ezhou, Ezhou city, Hubei Province, China.
Medicine (Baltimore). 2018 Oct;97(40):e12605. doi: 10.1097/MD.0000000000012605.
The use of fibular graft for the reconstruction of bone defects has been demonstrated to be a reliable method. The aim of this study was to assess the clinical outcome of graft union, functional outcome (hypertrophy of the graft bones) and complications of both non-vascularized and vascularized grafts.From 1981 to 2015, 10 patients were treated using non-vascularized fibular graft or free vascularized fibular graft. The outcomes were bony union time, graft hypertrophy and complications based on radiograph and functional outcomes according to the Musculoskeletal Tumor Society (MSTS) score. Mobility of the ankle at the donor site was evaluated using the Kofoed ankle score system.This study included 10 patients with an average follow-up of 6.8 years. The union rate for all patients was 100%. The mean union time was 21.3 weeks for vascularized fibular grafts and 30.5 weeks for non-vascularized fibular grafts (P = .310). There was a significant difference between the upper limbs and the lower limbs regarding hypertrophy of the grafts in 5 patients (P = .003). The mean MSTS score in 10 patients was 84% (range 53%-97%). Stress fracture of the graft occurred in 1 patient. Donor site complications, including valgus deformity and length discrepancy, between 2 legs occurred in 2 patients who were under 18 years of age at the time of operation (P = .114). The mean Kofoed score was 96.8 (range 88-100).A greater increase in hypertrophy of grafts was observed with reconstruction in the lower limbs. There was no difference in MSTS score between these 2 types of grafts. Children were more likely to experience the valgus deformity at the donor site after harvesting the fibula. Keeping at least the distal 1/4 of the fibula intact during the surgery is a valid means of ensuring ankle stability at the donor site, and children should be considered for prophylactic distal tibiofibular synostosis creation to prevent the valgus deformity of the ankle at the donor site.
腓骨移植用于骨缺损重建已被证明是一种可靠的方法。本研究的目的是评估非血管化和血管化移植的骨愈合临床结果、功能结果(移植骨肥大)及并发症。1981年至2015年,10例患者接受了非血管化腓骨移植或游离血管化腓骨移植治疗。结果指标包括基于X线片的骨愈合时间、移植骨肥大及并发症,以及根据肌肉骨骼肿瘤学会(MSTS)评分得出的功能结果。使用Kofoed踝关节评分系统评估供区踝关节的活动度。本研究纳入10例患者,平均随访6.8年。所有患者的愈合率为100%。血管化腓骨移植的平均愈合时间为21.3周,非血管化腓骨移植为30.5周(P = 0.310)。5例患者的移植骨肥大在上肢和下肢之间存在显著差异(P = 0.003)。10例患者的平均MSTS评分为84%(范围53% - 97%)。1例患者发生移植骨应力性骨折。2例手术时年龄小于18岁的患者出现供区并发症,包括外翻畸形和双腿长度差异(P = 0.114)。平均Kofoed评分为96.8(范围88 - 100)。下肢重建时观察到移植骨肥大增加更明显。这两种类型的移植在MSTS评分上没有差异。儿童在腓骨采集后供区更易出现外翻畸形。手术中保留至少腓骨远端1/4完整是确保供区踝关节稳定性的有效方法,对于儿童应考虑预防性行胫腓骨远端融合以防止供区踝关节外翻畸形。