Olmi P, Cellai E, Fallai C, Fargnoli R, Giannardi G, Simoncini R, Villari N
Dipartimento di Fisiopathologia Clinica-Università Firenze.
Radiol Med. 1991 Mar;81(3):327-31.
Ninety-seven patients affected with nasopharyngeal carcinoma (NPC) were examined with both conventional and Computed Tomography (CT) to evaluate the involved sites with both methods. CT staging was more accurate, showing involvement in more locations than conventional tomography, so that staging was modified in 23 of 97 patients. Two hundred and seventeen patients treated from 1970 to 1985 were subdivided into group A (111 patients who underwent conventional tomography only) and group B (106 patients examined with CT, from 1978 on). A trend toward more advanced stages at presentation was observed in group B; nevertheless, local control at 5 years was higher in group B (59%) than in group A (42%). The role of Magnetic Resonance (MR) imaging in NPC staging was also evaluated in 30 patients: there was disagreement in 2 cases. Involvement of different structures was shown in 10 of 28 cases with the same CT and MR staging. MR imaging proved a valuable tool in the follow-up as well: in fact, it clarified 12 questionable opacities on CT in a group of 35 followed patients as inflammatory lesions in 10 patients and tumors in 2.
对97例鼻咽癌(NPC)患者进行了传统检查和计算机断层扫描(CT),以评估两种方法所显示的受累部位。CT分期更准确,显示受累部位比传统断层扫描更多,因此97例患者中有23例的分期被修改。将1970年至1985年接受治疗的217例患者分为A组(仅接受传统断层扫描的111例患者)和B组(1978年起接受CT检查的106例患者)。B组患者初诊时病情有更晚期的趋势;然而,B组5年局部控制率(59%)高于A组(42%)。还对30例患者评估了磁共振(MR)成像在NPC分期中的作用:有2例存在分歧。在28例CT和MR分期相同的病例中,有10例显示不同结构受累。MR成像在随访中也被证明是一种有价值的工具:事实上,在一组35例接受随访的患者中,它明确了CT上12处可疑的混浊区域,其中10例为炎性病变,2例为肿瘤。