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[不同剂量率快中子辐照酿酒酵母细胞的遗传变化]

[Genetic changes in yeast cells Saccharomyces irradiated by fast neutrons with different dose rate].

作者信息

Malinova I V, Tsyb T S, Komarova E V

出版信息

Radiats Biol Radioecol. 2009 Nov-Dec;49(6):658-64.

Abstract

No neutron dose rate effects in the wide range of 10(-3) Gy/s to 10(6) Gy/s were observed in yeast diploid cells for induction of mitotic segregation and crossing-over. The RBE values for these effects were determined as doses ratio (Dgamma/D(n)) at maximum effects. The RBE were 2.2-1.9 for neutrons of the reactor BR-10 (E = = 0.85 MeV) and the pulse reactor BARS-6 (E = 1.44 MeV). The RBE values for genetic effects were 1.0 at the equal survival level for neutrons and gamma-rays 60Co.

摘要

在酵母二倍体细胞中,未观察到10⁻³ Gy/s至10⁶ Gy/s的宽剂量率范围内的中子剂量率对有丝分裂分离和交叉诱导的影响。这些效应的相对生物效应(RBE)值被确定为最大效应时的剂量比(Dγ/Dn)。对于BR-10反应堆(E = 0.85 MeV)和脉冲反应堆BARS-6(E = 1.44 MeV)的中子,RBE为2.2 - 1.9。在中子和⁶⁰Coγ射线同等存活水平下,遗传效应的RBE值为1.0。

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