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[关节挛缩症与母亲重症肌无力。复发风险]

[Arthrogryposis and maternal myasthenia gravis. Risk of recurrence].

作者信息

Tranchant C, Ehret C, Labouret P, Gasser B, Warter J M

机构信息

Clinique Neurologique, Centre Hospitalo-Universitaire de Strasbourg.

出版信息

Rev Neurol (Paris). 1991;147(1):62-4.

PMID:2014384
Abstract

A 26-year old myasthenic woman whose disease had been in remission for more than 4 years gave birth, at the end of 2 induced pregnancies, to 2 stillborn infants with arthrogryposis. The presence of inherited antibodies directed against acetylcholine receptors most probably does not explain the diffuse retractions. This case illustrates the risk of recurrent foetal arthrogryposis after a first abnormal pregnancy in women with myasthenia gravis.

摘要

一名26岁的重症肌无力女性,其病情已缓解超过4年,在两次人工诱导妊娠结束时,产下两名患有先天性多发性关节挛缩症的死产婴儿。针对乙酰胆碱受体的遗传性抗体的存在很可能无法解释弥漫性挛缩。该病例说明了重症肌无力女性首次异常妊娠后复发性胎儿先天性多发性关节挛缩症的风险。

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