类风湿关节炎的遗传。

Inheritance of rheumatoid arthritis.

机构信息

Dept. of Dermatology, Sahlgrenska Sjukhuset, Gothenburg, Sweden.

出版信息

Scand J Rheumatol. 1987;16(1):211-6. doi: 10.3109/03009747009165373.

PMID:20144111

Abstract

The inheritance of rheumatoid arthritis was investigated in three areas in Sweden where nearly the total population over the age of seven (22, 707 persons) was examined for the prevalence of rheumatoid arthritis (ARA-criteria). No significantly higher frequencies of rheumatoid arthritis were found among relatives of rheumatoid arthritics than among matched relatives of matched controls. The results are disappointing and throw no new light on possible inheritance of rheumatoid arthritis.

摘要

类风湿关节炎的遗传在瑞典的三个地区进行了研究，在这些地区，几乎所有年龄在七岁以上的人群（22,707 人）都接受了类风湿关节炎（ARA 标准）的患病率检查。类风湿关节炎患者的亲属中，类风湿关节炎的频率并没有明显高于匹配对照患者的亲属。结果令人失望，没有为类风湿关节炎的可能遗传提供新的线索。