Matsuura Toshiki, Sugihara Kazuhiro, Kohmura Yasuhiro, Sugimura Haruhiko, Kanayama Naohiro
Department of Obstetrics and Gynecology, Hamamatsu University School of Medicine, Hamamatsu, Japan.
J Obstet Gynaecol Res. 2009 Dec;35(6):1142-7. doi: 10.1111/j.1447-0756.2009.01074.x.
Cases of cancer presenting with microscopically confirmed metastatic malignancies for which no primary site can be detected are a challenge to stage clinically. Adenocarcinoma of unknown primary site is a subtype with high frequency that has no standard treatment and a poor prognosis. A 32-year-old female was found to have a tumor in the abdominal wall. Tumorectomy was conducted. A pathological examination indicated serous papillary adenocarcinoma, and peritoneal or ovarian cancer was suspected. Exploratory laparotomy and partial resection of the ovaries were carried out, but there were no malignant findings in the peritoneum, ovarian tissue or ascitic fluid. This is an extremely rare case of serous papillary adenocarcinoma with a cystic tumor that was categorized as extraovarian peritoneal serous papillary carcinoma (EPSPC) without other clinical findings.
临床上,对于那些经显微镜检查确诊为转移性恶性肿瘤但无法检测到原发部位的癌症病例,进行分期是一项挑战。原发部位不明的腺癌是一种高频亚型,没有标准治疗方法且预后较差。一名32岁女性被发现腹壁有肿瘤。进行了肿瘤切除术。病理检查显示为浆液性乳头状腺癌,怀疑为腹膜或卵巢癌。进行了剖腹探查和卵巢部分切除术,但在腹膜、卵巢组织或腹水中未发现恶性病变。这是一例极其罕见的伴有囊性肿瘤的浆液性乳头状腺癌病例,被归类为卵巢外腹膜浆液性乳头状癌(EPSPC),无其他临床表现。