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卵巢外腹膜浆液性乳头状癌:一例报告

Extraovarian peritoneal serous papillary carcinoma: a case report.

作者信息

Veroni Sophia, Terzopoulou Kalliopi, Anagnostopoulou Irene, Vassilakaki Thivi, Grammatoglou Xanthippi, Rammou Rea

机构信息

Department of Cytopathology, "Tzanio" General Hospital of Pireas, Afentouli and Zanni, 18536 Pireas, Greece.

出版信息

Acta Cytol. 2010 Sep-Oct;54(5 Suppl):879-84.

Abstract

BACKGROUND

Extraovarian peritoneal serous papillary carcinoma (EPSPC) is a rare cancer closely related to ovarian carcinoma and characterized by abdominal carcinomatosis without an identifiable abdominal primary tumor.

CASE

A woman presented with ascites. She had an elevated serum CA-125. Peritoneal carcinomatosis without involvement of the ovaries was found. Paracentesis of the ascitic fluid resulted in a positive cytologic report not further suggestive of the malignancy origin, balancing between a mesothelioma and an adenocarcinoma. The histologic and immunohistochemical study of peritoneal biopsy specimens resulted in the diagnosis of EPSPC.

CONCLUSION

The combination of cytology, histology, immunohistochemistry and clinical data is a reliable method for the preoperative diagnosis of EPSPC, allowing prompt chemotherapy as surgery may not be indicated in most cases.

摘要

背景

卵巢外腹膜浆液性乳头状癌(EPSPC)是一种罕见的癌症,与卵巢癌密切相关,其特征是存在腹部癌性播散但未发现可识别的腹部原发性肿瘤。

病例

一名女性出现腹水。她的血清CA-125升高。发现存在未累及卵巢的腹膜癌性播散。腹水穿刺获得的细胞学报告呈阳性,但未进一步提示恶性肿瘤的起源,难以区分是间皮瘤还是腺癌。腹膜活检标本的组织学和免疫组化研究确诊为EPSPC。

结论

细胞学、组织学、免疫组化和临床资料相结合是术前诊断EPSPC的可靠方法,由于大多数情况下可能不适合手术,因此可据此及时进行化疗。

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