Department of Cell Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
Cell. 2010 Feb 5;140(3):310-2. doi: 10.1016/j.cell.2010.01.035.
The acquisition of fertilization capacity by sperm is regulated by intracellular pH (pH(i)), but the transport pathways that regulate pH(i) are not well understood. Lishko et al. (2010) now report that Hv1, the voltage-sensitive proton channel, is present in human sperm and is an important regulator of the functional maturation of sperm.
精子受精能力的获得受细胞内 pH 值(pH(i))的调节,但调节 pH(i)的转运途径尚不清楚。Lishko 等人(2010 年)现在报告说,Hv1(电压敏感性质子通道)存在于人类精子中,是精子功能成熟的重要调节因子。