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口服青蒿琥酯治疗新生儿疟疾。

Oral artesunate for neonatal malaria.

机构信息

Department of Paediatrics, Fr Muller Medical College, Mangalore, Karnataka, India.

出版信息

J Trop Pediatr. 2010 Dec;56(6):452-3. doi: 10.1093/tropej/fmq007. Epub 2010 Feb 8.

Abstract

A 24-day male baby presented with a history of fever and poor feeding. The baby was pale and had hepatosplenomegaly. Peripheral blood films revealed Plasmodium vivax. Chloroquine is the drug of choice in neonatal malaria. However, our patient did not respond to chloroquine. There has been very little experience with other drugs. This case highlights the use of oral artesunate to which the baby responded. The future may see its more frequent use in resistant malaria.

摘要

一名 24 天大的男婴因发热和喂养不良就诊。患儿面色苍白,肝脾肿大。外周血涂片显示间日疟原虫感染。氯喹是新生儿疟疾的首选药物。然而,我们的患者对氯喹没有反应。其他药物的经验非常有限。本病例强调了使用青蒿琥酯口服治疗的效果,患儿对此有反应。未来可能会更频繁地使用青蒿琥酯治疗耐药性疟疾。

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