Godino C, Carlino M, Al-Lamee R, Colombo A
San Raffaele Scientific Institute, Milan, Italy.
Minerva Cardioangiol. 2010 Feb;58(1):41-60.
Percutaneous coronary intervention (PCI) for chronic total occlusions (CTO) remains a major challenge in interventional cardiology. Successful recanalization of a CTO can alleviate angina, reduce the need for coronary artery bypass surgery and increase long-term survival. Improving results from the historically quoted success rates of 50% to the levels now routinely quoted by some operators (80-90%), requires not just skill and experience, but also a thorough understanding of the wide array of materials and techniques now available in this area. The decision to attempt PCI of a CTO (versus continued medical therapy or surgical revascularization) requires an individualized risk/benefit analysis, encompassing clinical, imaging and technical considerations.
对慢性完全闭塞病变（CTO）进行经皮冠状动脉介入治疗（PCI）仍是介入心脏病学中的一项重大挑战。成功使CTO再通可缓解心绞痛、减少冠状动脉旁路移植术的需求并提高长期生存率。要将以往报道的50%的成功率提高到现在一些术者常规报道的水平（80 - 90%），不仅需要技巧和经验，还需要全面了解该领域现有的各种材料和技术。决定尝试对CTO进行PCI（相对于继续药物治疗或外科血运重建）需要进行个体化的风险/获益分析，包括临床、影像学和技术方面的考虑因素。
