Avgustinovich D F, Kovalenko I L
Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, 10 Lavrent'ev Prospekt, 630090, Novosibirsk, Russia.
Neurosci Behav Physiol. 2010 Mar;40(3):257-62. doi: 10.1007/s11055-010-9252-1. Epub 2010 Feb 10.
The behavior of male and female C57BL/6J mice was studied after prolonged psychoemotional stress imposed by enforced cohabitation with an aggressive male on the other side of a partition in the cage and daily witnessing of 10-minute confrontations between the aggressor and another male placed with it. The elevated plus maze test demonstrated marked anxiety in mice of both genders after one month of psychoemotional stress. However, only females, but not males, showed an increase in the duration of passive swimming in the Porsolt test, along with some reduction in communicativeness in the partition test. Thus, these studies showed a more marked reaction to prolonged pscyhoemotional stress in females than in males.
通过将雄性C57BL/6J小鼠与一只具有攻击性的雄性小鼠隔着笼子隔板强制同居，并每天目睹攻击者与另一只与其共处的雄性小鼠进行10分钟的对抗，对其施加长期的心理情绪压力后，研究了雄性和雌性C57BL/6J小鼠的行为。高架十字迷宫试验表明，经过一个月的心理情绪压力后，两种性别的小鼠均表现出明显的焦虑。然而，在波索尔特试验中，只有雌性小鼠的被动游泳时间增加，同时在隔板试验中的交流性有所降低，而雄性小鼠则没有这些变化。因此，这些研究表明，雌性小鼠对长期心理情绪压力的反应比雄性小鼠更为明显。
